Dean Kimberley Rose, Koirala Archana, Samarasekara Harsha
Resident Medical Officer, Orange Health Service of Western NSW Local Health District, 1530 Forest Road, Orange, NSW 2800, Australia.
Staff Specialist in Immunology and Paediatrics, New South Wales Immunisation Specialist Service (NSWISS) Team, Nepean Blue Mountains Local Health District, Derby St., Kingswood, NSW 2747, Australia.
Access Microbiol. 2023 Jul 17;5(7). doi: 10.1099/acmi.0.000611.v3. eCollection 2023.
is a highly virulent, vaccine-preventable pathogen which can cause disease on a spectrum from benign to fatal. Apart from pneumonia, it commonly causes septicaemia and meningitis. This case report describes an unusual range of complications in a 53-year-old Caucasian female presenting to a regional hospital, without any risk known factors for severe disease (such as extremes of age, immunodeficiency or co-morbidities). Progressing from an episode of otitis media, her condition rapidly progressed to mastoid sinusitis, septic arthritis, infective endocarditis, epidural abscesses and multiple subcutaneous abscesses. Following quick identification of from a positive blood culture, the patient was treated with high-dose benzylpenicillin and ceftriaxone and aggressive source control by surgery, enabling a good clinical recovery.
是一种高致病性、可通过疫苗预防的病原体，可导致从良性到致命的一系列疾病。除了肺炎，它通常还会引起败血症和脑膜炎。本病例报告描述了一名53岁白种女性在一家地区医院出现的一系列不寻常并发症，该女性没有任何已知的严重疾病风险因素（如年龄极端、免疫缺陷或合并症）。从一次中耳炎发作开始，她的病情迅速发展为乳突窦炎、化脓性关节炎、感染性心内膜炎、硬膜外脓肿和多处皮下脓肿。在通过阳性血培养快速鉴定出病原体后，患者接受了大剂量苄星青霉素和头孢曲松治疗，并通过手术进行积极的源头控制，从而实现了良好的临床康复。
