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免疫功能正常患者的肺炎链球菌性脊髓硬膜外脓肿

Streptococcus pneumoniae Spinal Epidural Abscess in an Immunocompetent Patient.

作者信息

Sinnasone Salena, Blyth Michelle

机构信息

School of Medicine, Louisiana State University Health Sciences Center, New Orleans, USA.

Infectious Disease, Tulane University School of Medicine, New Orleans, USA.

出版信息

Cureus. 2024 Sep 5;16(9):e68710. doi: 10.7759/cureus.68710. eCollection 2024 Sep.

Abstract

Epidural abscesses are a rare diagnosis in immunocompetent patients. The most common risk factors linked with spinal epidural abscesses are intravenous drug use, diabetes mellitus, hepatitis, and iatrogenic factors like prior surgery and catheter usage. The thoracic and lumbar spine are the most common sites of these abscesses. Clinical presentation can include back pain, fever, and neurologic deterioration, with back pain occurring in almost two-thirds of patients. is the most common causative pathogen. We present a 50 male with no significant past medical or family history who presented with progressive back pain for greater than one week, chills and malaise. Cervical and lumbar spinal CT scans identified epidural abscesses at C6/7 and L5/S1. Blood cultures and surgical cultures from washout of the epidural space grew . The patient was treated successfully with a prolonged course of cefazolin for six weeks. is a rare cause of epidural abscesses, especially in patients with no known risk factors for invasive disease. This case demonstrates that invasive pneumococcal disease should remain on the differential diagnosis even in immunocompetent patients.

摘要

在免疫功能正常的患者中,硬膜外脓肿是一种罕见的诊断。与脊柱硬膜外脓肿相关的最常见危险因素是静脉注射毒品、糖尿病、肝炎以及诸如既往手术和使用导管等医源性因素。胸段和腰段脊柱是这些脓肿最常见的部位。临床表现可包括背痛、发热和神经功能恶化,几乎三分之二的患者会出现背痛。 是最常见的致病病原体。我们报告一例50岁男性,既往无重大病史或家族史,出现进行性背痛超过一周,伴有寒战和不适。颈椎和腰椎CT扫描显示C6/7和L5/S1处有硬膜外脓肿。血液培养以及硬膜外腔冲洗的手术培养结果显示 。该患者接受了为期六周的头孢唑林长期治疗并成功治愈。 是硬膜外脓肿的罕见病因,尤其是在没有已知侵袭性疾病危险因素的患者中。该病例表明,即使在免疫功能正常的患者中,侵袭性肺炎球菌疾病也应保留在鉴别诊断范围内。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f46/11453147/93a4f680edb6/cureus-0016-00000068710-i01.jpg

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