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通过肾造瘘管灌注氟康唑成功治疗输尿管支架相关真菌球。

Successful treatment of ureteral-stent-related fungal ball using fluconazole instillation through a nephrostomy tube.

作者信息

Chacko Arman Z, Misra Soumya

机构信息

Department of Urology, Royal Devon University Healthcare NHS Foundation Trust, Raleigh Heights, Barnstaple, EX31 4JB, United Kingdom.

出版信息

Urol Case Rep. 2023 Aug 2;50:102522. doi: 10.1016/j.eucr.2023.102522. eCollection 2023 Sep.

DOI:10.1016/j.eucr.2023.102522
PMID:37601835
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10433036/
Abstract

The kidneys are the most common solid organ to be infected by Candida sp. And may occur due to hematogenous spread, ascending infection, or with the presence of stent and nephrostomy tubes. Evidence for treatment is limited to case reports. We successfully cleared a candida infection of a ureteric stent in a 35-year-old diabetic gentleman by instilling 300 mg of fluconazole in 500 mL of normal saline over 8 hours once daily for 7 days via the nephrostomy tube.

摘要

肾脏是最常被念珠菌属感染的实体器官，感染可能因血行播散、上行感染或存在支架及肾造瘘管而发生。治疗证据仅限于病例报告。我们通过经肾造瘘管每天一次、持续7天、在8小时内将300毫克氟康唑滴注于500毫升生理盐水中，成功清除了一名35岁糖尿病男性输尿管支架上的念珠菌感染。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1942/10433036/76ebc1224153/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1942/10433036/1135e060a58e/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1942/10433036/4596f0d5a7f0/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1942/10433036/76ebc1224153/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1942/10433036/1135e060a58e/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1942/10433036/4596f0d5a7f0/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1942/10433036/76ebc1224153/gr3.jpg

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本文引用的文献

1
Epidemiology and risk factors for ureteral stent-associated urinary tract infections in non-transplanted renal patients: a systematic review of the literature.非移植肾患者输尿管支架相关尿路感染的流行病学和危险因素：文献系统评价。
World J Urol. 2021 Oct;39(10):3845-3860. doi: 10.1007/s00345-021-03693-7. Epub 2021 May 15.
2
Treatment of Renal Fungal Ball with Fluconazole Instillation Through a Nephrostomy Tube: Case Report and Literature Review.经肾造瘘管灌注氟康唑治疗肾真菌球：病例报告及文献复习
Am J Case Rep. 2018 Oct 4;19:1179-1183. doi: 10.12659/AJCR.911113.
3
Management of Candida biofilms: state of knowledge and new options for prevention and eradication.
念珠菌生物膜的管理：知识现状和预防及清除的新选择。
Future Microbiol. 2016;11(2):235-51. doi: 10.2217/fmb.15.139. Epub 2016 Feb 5.
4
Clinical Practice Guideline for the Management of Candidiasis: 2016 Update by the Infectious Diseases Society of America.《念珠菌病管理临床实践指南：美国传染病学会2016年更新版》
Clin Infect Dis. 2016 Feb 15;62(4):e1-50. doi: 10.1093/cid/civ933. Epub 2015 Dec 16.