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新冠病毒病康复者的颅神经受累情况。

Cranial nerve involvement among COVID-19 survivors.

作者信息

Heidari Mohammad Eghbal, Nazemi Pershang, Feizabad Elham, Beiranvand Farzaneh, Afzali Mahdieh

机构信息

Student's Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran.

Yas Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.

出版信息

Front Neurol. 2023 Aug 4;14:1182543. doi: 10.3389/fneur.2023.1182543. eCollection 2023.

DOI:10.3389/fneur.2023.1182543
PMID:37602247
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10436332/
Abstract

INTRODUCTION

COVID-19 was first reported in November 2019 in China and rapidly spread across the globe. COVID-19 causes neurologic symptoms and complications, which may persist even after recovery in patients. The objective of this research was to determine the involvement of cranial nerves in COVID-19 survivors.

METHOD

This was a retrospective study. The study was conducted between March and July of 2022. The analysis included 98 patients with a certain positive polymerase chain reaction. SPSS software version 19 was utilized for data analysis.

RESULTS

The average age of the participants was 40.47 years (8.81). The olfactory nerve was found to be the most frequently involved cranial nerve (36.7%). Over 20% of participants had a taste disorder. The findings from the regression analysis indicated that lung involvement and age have a direct and significant relationship with cranial nerve involvement and can serve as its predictors ( = 0.001).

CONCLUSION

It seems that cranial nerve involvement was sustained in COVID-19 patients who survived. In addition, elderly patients and patients with severe illnesses were more likely to show cranial symptoms. It is necessary to monitor COVID-19 survivors for neurological symptoms.

摘要

引言

2019年11月首次在中国报告了新型冠状病毒肺炎(COVID-19),并迅速在全球传播。COVID-19会引发神经症状和并发症,即使患者康复后这些症状仍可能持续存在。本研究的目的是确定COVID-19康复者的颅神经受累情况。

方法

这是一项回顾性研究。研究于2022年3月至7月进行。分析纳入了98例聚合酶链反应呈阳性的患者。使用SPSS 19版软件进行数据分析。

结果

参与者的平均年龄为40.47岁(8.81)。发现嗅神经是最常受累的颅神经(36.7%)。超过20%的参与者有味觉障碍。回归分析结果表明,肺部受累和年龄与颅神经受累有直接且显著的关系,可作为其预测指标(P = 0.001)。

结论

似乎COVID-19康复患者存在持续的颅神经受累情况。此外,老年患者和重症患者更易出现颅神经症状。有必要对COVID-19康复者进行神经症状监测。