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COVID-19 相关颅神经病变的磁共振成像特征。

Magnetic resonance imaging features of COVID-19-related cranial nerve lesions.

机构信息

Clínica de Diagnóstico Por Imagem (CDPI)/DASA, Avenida das Américas, 4666, 302A, 303, 307, 325, 326, Barra da Tijuca, Rio de Janeiro, RJ, 2640-102, Brazil.

NEUROCOVID-RIO Group-Research Group On Neurological Syndromes Associated With SARS-CoV-2, Rio de Janeiro, Brazil.

出版信息

J Neurovirol. 2021 Feb;27(1):171-177. doi: 10.1007/s13365-020-00934-0. Epub 2021 Jan 18.

Abstract

The complete features of the neurological complications of coronavirus disease 2019 (COVID-19) still need to be elucidated, including associated cranial nerve involvement. In the present study we describe cranial nerve lesions seen in magnetic resonance imaging (MRI) of six cases of confirmed COVID-19, involving the olfactory bulb, optic nerve, abducens nerve, and facial nerve. Cranial nerve involvement was associated with COVID-19, but whether by direct viral invasion or autoimmunity needs to be clarified. The development of neurological symptoms after initial respiratory symptoms and the absence of the virus in the cerebrospinal fluid (CSF) suggest the possibility of autoimmunity.

摘要

新冠病毒病 2019(COVID-19)的神经系统并发症的全部特征仍需阐明,包括相关颅神经受累。在本研究中,我们描述了 6 例确诊 COVID-19 患者的磁共振成像(MRI)所见颅神经病变,涉及嗅球、视神经、外展神经和面神经。颅神经受累与 COVID-19 有关,但通过直接病毒入侵还是自身免疫需要阐明。初始呼吸道症状后出现神经系统症状以及脑脊液(CSF)中无病毒提示存在自身免疫的可能性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bbcb/7812977/c5edf1b4d727/13365_2020_934_Fig1_HTML.jpg

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