破坏[具体内容]可挽救在可发酵碳源上的生长。 （你提供的原文中“Disruption of in ”有缺失信息，我按格式进行了翻译，可根据实际完整内容调整）
Disruption of in rescues growth on fermentable carbon sources.
作者信息
Chen Anqi, Gibney Patrick A
机构信息
Department of Food Science, Cornell University, Ithaca, New York, United States.
Science Center for Future Foods, Jiangnan University, Wuxi, Jiangsu, China.
出版信息
MicroPubl Biol. 2023 Aug 3;2023. doi: 10.17912/micropub.biology.000927. eCollection 2023.
In , trehalose-6-phosphate synthase (Tps1) catalyzes the formation of trehalose-6-phophate in trehalose synthesis. Deletion of the gene is associated with phenotypes including inability to grow on fermentable carbon sources, survive at elevated temperatures, or sporulate. To further understand these pleiotropic phenotypes, we conducted a genetic suppressor screen and identified a novel suppressor, Δ, able to restore Δ growth on rapidly fermentable sugars. However, disruption of did not rescue Δ thermosensitivity. These results support the model that trehalose metabolism has important roles in regulating glucose sensing and signaling in addition to regulating stress resistance.
在[具体情境未明确]中，海藻糖-6-磷酸合酶（Tps1）在海藻糖合成过程中催化海藻糖-6-磷酸的形成。该基因的缺失与多种表型相关，包括无法在可发酵碳源上生长、在高温下存活或形成孢子。为了进一步了解这些多效性表型，我们进行了遗传抑制子筛选，并鉴定出一种新型抑制子，即[具体基因缺失型未明确]Δ，它能够恢复[具体基因缺失型未明确]Δ在快速发酵糖类上的生长。然而，[具体基因未明确]的破坏并不能挽救[具体基因缺失型未明确]Δ的热敏感性。这些结果支持了这样一种模型，即海藻糖代谢除了调节抗逆性外，在调节葡萄糖感知和信号传导方面也具有重要作用。
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