Nakamura Keisuke, Kumagai Yukiko, Kobayashi Akihiro, Suzuki Minori, Yoshida Suguru
Department of Biological Science and Technology, Faculty of Advanced Engineering, Tokyo University of Science, 6-3-1 Niijuku, Katsushika-ku, Tokyo 125-8585, Japan.
Laboratory of Chemical Bioscience, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), 2-3-10 Kanda-Surugadai, Chiyoda-ku, Tokyo 101-0062, Japan.
Org Biomol Chem. 2023 Aug 30;21(34):6886-6891. doi: 10.1039/d3ob01108a.
A practical method to synthesize sulfinate esters from aryl iodides is disclosed. Direct oxidation of thioesters prepared by copper-catalyzed C-S formation of aryl iodides realized the efficient synthesis of sulfinate esters. Due to the good accessibility of aryl iodides, a wide variety of sulfinate esters were prepared from easily available starting materials such as carboxylic acids and anilines.
公开了一种由芳基碘化物合成亚磺酸酯的实用方法。通过铜催化芳基碘化物的C-S形成制备的硫酯直接氧化实现了亚磺酸酯的高效合成。由于芳基碘化物易于获得，因此可以从诸如羧酸和苯胺等容易获得的起始原料制备多种亚磺酸酯。
