The Department of Obstetrics and Gynecology, The Chaim Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel.
The Sackler School of Medicine Tel Aviv University, Tel Aviv, Israel.
J Perinat Med. 2023 Aug 21;52(1):22-29. doi: 10.1515/jpm-2023-0154. Print 2024 Jan 29.
To compare delivery outcomes of pregnancies diagnosed with placenta-accreta-syndrome (PAS) who underwent conservative treatment to patients who underwent cesarean hysterectomy.
A retrospective study of all women diagnosed with PAS treated in one tertiary medical center between 03/2011 and 11/2020 was performed. Comparison was made between conservative management during cesarean delivery and cesarean hysterectomy. Conservative management included leaving uterus with/without placenta and with/without myometrial resection.
A total of 249 pregnancies (0.25 % of all deliveries) were diagnosed with PAS, 208 underwent conservative cesarean delivery and 41 had cesarean hysterectomy, 31 of them were unplanned (75.6 %). The median number of previous cesarean deliveries was significantly higher in the cesarean hysterectomy group. There was no difference in the duration from the last cesarean delivery, the presence of placenta previa, pre-operative hemoglobin or platelets levels between the pregnancies with conservative management and the cesarean hysterectomy. Significantly more pregnancies with sonographic suspicion of placenta percreta and bladder invasion had cesarean hysterectomy. Cesarean hysterectomy was significantly associated with earlier delivery, with bleeding and required significantly more blood products. There was no statistically significant difference in the rate of relaparotomy following cesarean delivery or the rate of infections. Multivariable-regression-analysis revealed a significant odds ratio of 3.38 of blood loss of >3,000 mL following cesarean hysterectomy.
Conservative management in delivery of PAS pregnancies is associated with less bleeding complications during surgery compared to cesarean hysterectomy.
比较胎盘植入综合征(PAS)患者行保守治疗与行剖宫产子宫切除术的分娩结局。
对 2011 年 3 月至 2020 年 11 月在一家三级医疗中心接受 PAS 治疗的所有女性进行回顾性研究。比较剖宫产时保守治疗与剖宫产子宫切除术。保守治疗包括保留子宫伴/不伴胎盘和伴/不伴子宫肌层切除术。
共有 249 例(占所有分娩的 0.25%)妊娠被诊断为 PAS,其中 208 例行保守性剖宫产,41 例行剖宫产子宫切除术,其中 31 例为非计划性(75.6%)。剖宫产子宫切除术组的中位剖宫产次数明显更高。在保守治疗和剖宫产子宫切除术的妊娠中,最后一次剖宫产的时间、胎盘前置的存在、术前血红蛋白或血小板水平均无差异。超声疑胎盘穿透性植入和膀胱侵犯的妊娠更倾向于行剖宫产子宫切除术。剖宫产子宫切除术与更早的分娩、更多的出血和需要更多的血制品相关。剖宫产术后再次剖腹探查或感染的发生率无统计学差异。多变量回归分析显示,剖宫产子宫切除术的出血量>3000ml 的优势比为 3.38。
与剖宫产子宫切除术相比,PAS 患者分娩时行保守治疗与手术期间较少的出血并发症相关。