Shapera M R, Moel D I, Kamath S K, Olson R, Beauchamp G K
J Am Diet Assoc. 1986 Oct;86(10):1359-62, 1365.
Taste sensitivity and preference in the suprathreshold ranges were compared for 20 pediatric patients with renal disease and 15 children with normal renal function. Nine patients had chronic renal insufficiency, and 11 had endstage renal disease. Subjects were also evaluated for various dietary, anthropometric, and biochemical parameters. All subjects were asked to pull out a tape measure to rate the strength of five varying concentrations of aqueous solutions of sucrose, sodium chloride, and quinine sulfate. The subjects' abilities to judge increasing concentrations with greater perceived intensity were measured by calculating individual and group slopes. No significant differences in the values were found between the groups. Similarly, no significant differences in mean peak preference concentrations were found between the groups. The patients with renal disease were found to be considerably growth retarded (height and weight less than 5th percentile), with a mean caloric intake less than 65% of the RDA even after an adjustment had been made for height. Serum zinc levels were all normal.
对20名肾病患儿和15名肾功能正常的儿童进行了超阈值范围内味觉敏感性和偏好性的比较。9名患者患有慢性肾功能不全，11名患有终末期肾病。还对受试者的各种饮食、人体测量和生化参数进行了评估。所有受试者都被要求拉出卷尺，对蔗糖、氯化钠和硫酸奎宁的五种不同浓度水溶液的强度进行评分。通过计算个体和组斜率来测量受试者判断浓度增加且强度感知增强的能力。两组之间的值没有显著差异。同样，两组之间的平均峰值偏好浓度也没有显著差异。发现肾病患者生长明显迟缓（身高和体重低于第5百分位数），即使在根据身高进行调整后，平均热量摄入仍低于推荐膳食摄入量的65%。血清锌水平均正常。
