Watson A R, Stuart A, Wells F E, Houston I B, Addison G M
Hum Nutr Clin Nutr. 1983 May;37(3):219-25.
Diminished taste acuity (hypogeusia) and zinc deficiency have been reported in children on maintenance haemodialysis and with varying degrees of chronic renal failure. We have studied the effect of 6 weeks' zinc supplementation in 20 children with chronic renal impairment using a double-blind crossover trial. Although we achieved significant increases in serum zinc levels no significant improvement in taste acuity could be demonstrated. These studies provide no support for the belief that routine zine supplements are necessary in children with chronic renal failure.
据报道，接受维持性血液透析以及患有不同程度慢性肾衰竭的儿童存在味觉敏锐度下降（味觉减退）和锌缺乏的情况。我们采用双盲交叉试验，研究了20名慢性肾功能损害儿童补充锌6周的效果。尽管我们使血清锌水平显著升高，但味觉敏锐度并未得到显著改善。这些研究并不支持慢性肾衰竭儿童需要常规补锌的观点。
