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血液透析水中的微塑料和纳米塑料:新兴威胁,值得我们关注。

Microplastics and nanoplastics in haemodialysis waters: Emerging threats to be in our radar.

机构信息

Environmental Management Coordination and Environmental Technology and Bioprocesses Research Group, Federal Institute of Education, Science and Technology of Pernambuco, Av. Prof. Luís Freire, 500 - Cidade Universitária, Recife 50740-545, Brazil; Department of Civil, Environmental and Geomatic Engineering, University College London, London WC1E 6BT, United Kingdom.

UCL Department of Renal Medicine, Royal Free Hospital, University College London, London NW3 2PF, United Kingdom.

出版信息

Environ Toxicol Pharmacol. 2023 Sep;102:104253. doi: 10.1016/j.etap.2023.104253. Epub 2023 Aug 20.

DOI:10.1016/j.etap.2023.104253
PMID:37604358
Abstract

Microplastics are present in the environment, in drinking water, in human blood and there is evidence of nanoplastics in tap water. The objective of this work was to analyze the possibility of hemodialysis patients being contaminated by micro and nanoplastics (MNPs) during dialysis treatment. The motivation for this investigation is the fact that hemodialysis patients use about 300-600 L of drinking water per week, which may be contaminated by MNPs. A literature review, a field investigation in a London hospital and an estimation of MNPs intake in patients were carried out. The results showed potential points of risk of contamination of patients by MNPs in hemodialysis. It was also estimated that for a filtration efficiency of 99 % for MNPs, the amount of microplastics that can penetrate the kidneys of patients is 0.0021-3768 particles/week. The assessment concludes that hemodialysis patients are at high risk of MNP contamination.

摘要

微塑料存在于环境、饮用水中,并且有证据表明自来水中存在纳米塑料。本工作的目的是分析在透析治疗过程中血液透析患者是否会被微塑料和纳米塑料(MNPs)污染。进行这项调查的动机是血液透析患者每周使用约 300-600 升饮用水,这些水可能受到 MNPs 的污染。进行了文献综述、伦敦一家医院的实地调查以及对患者摄入 MNPs 的估计。结果表明,血液透析患者存在 MNPs 污染的潜在风险点。研究还估计,对于 MNPs 的过滤效率为 99%,能够穿透患者肾脏的微塑料数量为每周 0.0021-3768 个颗粒。评估得出结论,血液透析患者有很高的 MNPs 污染风险。

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