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非体外循环冠状动脉血运重建转换为体外循环手术的预测因素:一项回顾性分析。

Predicting Determinants for Conversion of Off-Pump Coronary Revascularization to On-Pump Surgery: A Retrospective Analysis.

作者信息

Kumar Chandranshu, K Sridartha, Bhushan Rahul, Grover Vijay, Jhajhria Narender S, Aiyer Palash V

机构信息

Cardiothoracic Surgery, Dr. Ram Manohar Lohia Hospital, New Delhi, IND.

出版信息

Cureus. 2023 Jul 21;15(7):e42258. doi: 10.7759/cureus.42258. eCollection 2023 Jul.

Abstract

A global consensus has not yet been reached regarding the preference for off-pump versus on-pump coronary revascularization. Although the coronary trial indicates that the secondary endpoint outcomes favor on-pump surgery, the cost-effectiveness and significantly lower immediate and early complications in off-pump surgery make it favorable for the Indian population. To analyze patients who underwent coronary revascularization, specifically coronary artery bypass grafting (CABG), a retrospective five-year study was conducted. During the given duration, a total of 652 patients underwent CABG. The study revealed a positive correlation between diabetes, high body surface area (BSA), and preexisting renal dysfunction as strong predictors for converting off-pump coronary artery bypass surgery (OPCABG) to on-pump surgery coronary artery bypass surgery (ONCABG). Preoperative electrocardiographic (ECG) changes and the use of intra-aortic balloon pulsation (IABP) as a mechanical assist device were strongly associated with the incidence of conversion from OPCABG to ONCABG. Tight left main disease and ostial coronary disease indicate a progressive dysfunction during off-pump surgery, necessitating early conversion to on-pump surgery to avoid complications. The on-pump group had more adverse outcomes in regard to renal and neurological dysfunction, which can be attributed to pump-induced dysfunction. In such scenarios, a surgeon's preparedness to convert an OPCABG to an ONCABG can be swift and efficient. In anticipation of increased pump-related complications in the ONCABG group, a measured approach can be implemented to avoid adverse postoperative outcomes in high-risk patients.

摘要

关于非体外循环与体外循环冠状动脉血运重建的偏好,尚未达成全球共识。尽管冠状动脉试验表明次要终点结果有利于体外循环手术,但非体外循环手术的成本效益以及显著更低的即刻和早期并发症使其对印度人群有利。为了分析接受冠状动脉血运重建的患者,特别是冠状动脉旁路移植术(CABG),进行了一项为期五年的回顾性研究。在给定期间,共有652例患者接受了CABG。研究显示,糖尿病、高体表面积(BSA)和既往存在的肾功能不全之间呈正相关,是将非体外循环冠状动脉旁路移植术(OPCABG)转换为体外循环冠状动脉旁路移植术(ONCABG)的有力预测因素。术前心电图(ECG)变化以及使用主动脉内球囊反搏(IABP)作为机械辅助装置与从OPCABG转换为ONCABG的发生率密切相关。左主干病变严重和冠状动脉开口病变表明非体外循环手术期间功能逐渐恶化,需要尽早转换为体外循环手术以避免并发症。体外循环组在肾脏和神经功能障碍方面有更多不良结局,这可归因于体外循环引起的功能障碍。在这种情况下,外科医生将OPCABG转换为ONCABG的准备可以迅速而有效。鉴于ONCABG组中与体外循环相关的并发症增加,可以采取审慎的方法来避免高危患者术后出现不良结局。

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