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冠状动脉疾病患者行体外循环与非体外循环冠状动脉旁路移植术的效果的倾向评分分析。

A propensity score analysis on the effect of on-pump versus off-pump coronary artery bypass grafting for patients with coronary artery disease.

机构信息

Cardiovascular center, China-Japan Friendship Hospital, Beijing 100029, China.

出版信息

J Thorac Dis. 2014 Jun;6(6):838-44. doi: 10.3978/j.issn.2072-1439.2014.05.08.

Abstract

AIM

The aim of this retrospective observational study was to investigate the effect of on-pump versus off-pump coronary artery bypass grafting (CABG) for patients with coronary artery diseases (CAD).

METHODS

A retrospective observational study was performed using a propensity score analysis in 290 consecutive patients undergoing CABG between April 2009 and March 2014, of them, 54 patients undergoing off-pump CABG (OPCABG) were matched with 54 patients undergoing on-pump CABG (ONCABG) by propensity score. The perioperative complications and hospital mortality were documented.

RESULTS

Preoperative characteristics were comparable in both groups following propensity matching. Postoperative myocardial infarction (MI) incidence was lower in OPCABG group than in ONCABG group (3.7% vs. 14.8%, P=0.046); both hospital mortality and the major complications rates were similar in the two groups after propensity adjustment for preoperative characteristics.

CONCLUSIONS

The perioperative complications are similar in both off-pump and on pump CABG groups, the short-term effect of OPCABG is similar to that of ONCABG.

摘要

目的

本回顾性观察研究旨在探讨体外循环与非体外循环冠状动脉旁路移植术(CABG)治疗冠状动脉疾病(CAD)患者的效果。

方法

采用倾向评分分析,对 2009 年 4 月至 2014 年 3 月期间连续接受 CABG 的 290 例患者进行回顾性观察研究,其中 54 例行非体外循环 CABG(OPCABG)的患者与 54 例行体外循环 CABG(ONCABG)的患者进行了倾向评分匹配。记录围手术期并发症和院内死亡率。

结果

倾向性评分匹配后两组患者的术前特征无差异。OPCABG 组术后心肌梗死(MI)发生率低于 ONCABG 组(3.7%比 14.8%,P=0.046);经术前特征倾向性调整后,两组患者的院内死亡率和主要并发症发生率相似。

结论

非体外循环与体外循环 CABG 两组的围手术期并发症相似,OPCABG 的短期效果与 ONCABG 相似。

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