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[ATLAS项目的现状与未来]

[Now and Future of the ATLAS Project].

作者信息

Nakamura Kenichi

机构信息

Dept. of International Clinical Development, National Cancer Center Hospital.

出版信息

Gan To Kagaku Ryoho. 2023 Aug;50(8):839-844.

Abstract

The National Cancer Center Hospital in Japan has established the Asia Cancer Clinical Trial Network, otherwise known as the ATLAS project, which began in September 2020 with government support. The goal of the ATLAS project is to foster a robust research platform for international clinical trials in Asia by developing research institutions' network and providing educational opportunities. The ATLAS project also aims to concurrently conduct multiple international clinical trials. Participating countries include not only longstanding collaborators such as Korea, Taiwan, and Singapore, but also rapidly developing nations such as Thailand, Malaysia, the Philippines, and Vietnam. Each country's top-tier research institutions have joined as participating facilities in the ATLAS project. Currently, 5 international clinical trials are ongoing with several more in preparation. While academia lacked an infrastructure to support such a lot of international research previously, the National Cancer Center Hospital has been addressing this by establishing the Department of International Clinical Development in November 2020, and operating the Asian Partnerships Office in Bangkok, Thailand from December 2021. This strategy is aimed at creating an in-house research support function to conduct affordable, swift, and convenient Asian collaborative clinical trials. Furthermore, to increase commitment to ATLAS across Asian countries, an ATLAS board has been established as a decision- making body as the clinical trial group. This mechanism, constructed to make decisions on a pan-Asian basis, is represented by 2 delegates from each country.

摘要

日本国立癌症中心医院建立了亚洲癌症临床试验网络,即所谓的ATLAS项目,该项目于2020年9月在政府支持下启动。ATLAS项目的目标是通过发展研究机构网络并提供教育机会,为亚洲的国际临床试验培育一个强大的研究平台。ATLAS项目还旨在同时开展多项国际临床试验。参与国家不仅包括韩国、台湾和新加坡等长期合作伙伴,还包括泰国、马来西亚、菲律宾和越南等快速发展的国家。每个国家的顶级研究机构都已作为参与机构加入了ATLAS项目。目前,有5项国际临床试验正在进行,还有几项正在筹备中。虽然此前学术界缺乏支持如此大量国际研究的基础设施,但国立癌症中心医院通过在2020年11月设立国际临床开发部,并于2021年12月在泰国曼谷运营亚洲合作办公室来解决这一问题。这一策略旨在创建一个内部研究支持功能,以开展经济、快速且便捷的亚洲合作临床试验。此外,为了提高亚洲各国对ATLAS项目的投入,已设立了一个ATLAS委员会作为临床试验组的决策机构。这一机制旨在在泛亚洲基础上做出决策,每个国家由2名代表参与。

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