Department of International Clinical Development, National Cancer Center Hospital, Tokyo, Japan.
Department of Medical Oncology, National Cancer Center Hospital, Tokyo, Japan.
Jpn J Clin Oncol. 2023 Jun 29;53(7):619-628. doi: 10.1093/jjco/hyad033.
This report summarizes the presentations and discussions in the first Asian Clinical Trials Network for Cancers (ATLAS) international symposium that was held on 24 April 2022, in Bangkok, Thailand, and hosted by the National Cancer Center Hospital (NCCH), co-hosted by the Pharmaceuticals and Medical Devices Agency (PMDA), Clinical Research Malaysia (CRM) and the Thai Society of Clinical Oncology (TSCO), and supported by Embassy of Japan in Thailand. Since 2020, the NCCH has conducted the ATLAS project to enhance research environments and infrastructures to facilitate international clinical research and cancer genomic medicine in the Asian region. The purpose of the symposium was to discuss what we can achieve under the ATLAS project, to share the latest topics and common issues in cancer research and to facilitate mutual understanding. Invitees included stakeholders from academic institutions, mainly at ATLAS collaborative sites, as well as Asian regulatory authorities. The invited speakers discussed ongoing collaborative research, regulatory perspectives to improve new drug access in Asia, the status of phase I trials in Asia, the introduction of research activities at the National Cancer Center (NCC) and the implementation of genomic medicine. As the next steps after this symposium, the ATLAS project will foster increased cooperation between investigators, regulatory authorities and other stakeholders relevant to cancer research, and establish a sustainable pan-Asian cancer research group to increase the number of clinical trials and deliver novel drugs to patients with cancer in Asia.
本报告总结了 2022 年 4 月 24 日在泰国曼谷举行的第一届亚洲临床试验网络癌症(ATLAS)国际研讨会的演讲和讨论情况,该研讨会由日本驻泰国大使馆提供支持,由国家癌症中心医院(NCCH)主办,药品和医疗器械管理局(PMDA)、马来西亚临床研究(CRM)和泰国临床肿瘤学会(TSCO)共同主办。自 2020 年以来,NCCH 一直在开展 ATLAS 项目,以加强研究环境和基础设施,促进亚洲地区的国际临床研究和癌症基因组医学。研讨会的目的是讨论在 ATLAS 项目下我们可以实现什么,分享癌症研究的最新主题和共同问题,并促进相互理解。邀请的与会者包括来自学术机构的利益相关者,主要是 ATLAS 合作地点的利益相关者,以及亚洲监管机构。受邀演讲者讨论了正在进行的合作研究、改善亚洲新药准入的监管观点、亚洲 I 期试验的现状、国家癌症中心(NCC)研究活动的介绍以及基因组医学的实施。作为本次研讨会的后续步骤,ATLAS 项目将促进研究人员、监管机构和其他与癌症研究相关的利益相关者之间的合作增加,并建立一个可持续的泛亚洲癌症研究小组,以增加亚洲癌症患者的临床试验数量并为其提供新药。