Tsakos Elias, Xydias Emmanouil M, Ziogas Apostolos C, Tsagias Nikolaos, Pappa Konstantina, Stergioula Afroditi, Bimpa Kanelina
Obstetrics and Gynaecology, EmbryoClinic IVF, Thessaloniki, GRC.
Medicine, School of Health Sciences, University of Thessaly, Larissa, GRC.
Cureus. 2023 Aug 20;15(8):e43827. doi: 10.7759/cureus.43827. eCollection 2023 Aug.
Assisted reproduction technology (ART) has made considerable progress in recent years; in particular with regard to cryopreservation, long-term storage, successful thawing, and embryo transfer of cryopreserved embryos. Regarding gestational surrogacy, progress has been made in the areas of awareness, social acceptance, regulation, legislation, availability, streamlining, and optimization of cross-border care. The above is being highlighted in the current presentation of a particularly challenging and novel case. A 43-year-old woman visited our clinic in Greece, seeking international gestational surrogacy due to recurrent breast cancer which rendered her medically unfit for pregnancy. Ten years before her initial visit to our clinic the patient had undergone fertility preservation due to breast cancer, her oocytes had been fertilized with her husband's sperm, and the embryos were cryopreserved and stored in a fertility clinic based in the United Kingdom. The stored embryos were transported to Greece, thawed, and successfully implanted to the selected gestational surrogate. Following an uneventful pregnancy, the surrogate delivered a healthy girl. This successful outcome exemplified innovation, motivation, and hope and may represent a paradigm of team scientific excellence associated with positive patient outcomes. Furthermore, this case constitutes the successful culmination of major advances made in various different sectors of cross-border reproductive care; laboratory, clinical, legal, ethical, and logistical.
近年来，辅助生殖技术（ART）取得了长足的进步；特别是在冷冻保存、长期储存、成功解冻以及冷冻胚胎的胚胎移植方面。关于代孕，在跨境医疗的认知、社会接受度、监管、立法、可及性、流程简化和优化等领域都取得了进展。在当前一个特别具有挑战性的新颖案例介绍中，上述情况得到了突出体现。一名43岁的女性前往我们位于希腊的诊所，由于复发性乳腺癌导致她在医学上不宜怀孕，她寻求国际代孕。在她首次就诊于我们诊所的十年前，该患者因乳腺癌进行了生育力保存，她的卵母细胞与丈夫的精子受精，胚胎被冷冻保存并储存在英国的一家生育诊所。储存的胚胎被运往希腊，解冻后成功植入选定的代孕母亲体内。经过顺利的孕期后，代孕母亲生下了一个健康的女孩。这一成功结果体现了创新、动力和希望，可能代表了与积极的患者结局相关的团队科学卓越典范。此外，该案例构成了跨境生殖医疗各个不同领域（实验室、临床、法律、伦理和后勤）取得重大进展的成功 culmination（此处原文culmination未给出准确释义，推测为“成果”之类的意思）。
