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创伤后孕妇的母婴结局:英格兰和威尔士创伤登记处的回顾性研究。

Maternal outcomes of pregnant patients after trauma: a retrospective study of the Trauma Registry of England and Wales.

机构信息

East Suffolk and North Essex NHS Foundation Trust, UK.

School of Medicine, National Kapodistrian University of Athens, Greece.

出版信息

Ann R Coll Surg Engl. 2024 Feb;106(2):160-166. doi: 10.1308/rcsann.2023.0047. Epub 2023 Aug 23.

DOI:10.1308/rcsann.2023.0047
PMID:37609686
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10833001/
Abstract

INTRODUCTION

Trauma accounts for 20% of deaths in pregnant women. Injury characterisation and outcome in pregnant women following trauma is poorly described. To understand and inform optimum care of this key injury population, a study was conducted using the Trauma Audit Research Network (TARN) database.

METHODS

In total, 341 pregnant and 26,774 non-pregnant female patients aged 15 to 46 years were identified for comparison from the TARN database. Mortality, cross-sectional imaging, blood product administration and EQ-5D scores were compared between the two groups. Mechanism of injury, Injury Severity Score (ISS) and mortality rate before and after the creation of regional trauma networks were reported for pregnant patients.

RESULTS

Pregnancy was recorded in 1.3% (341/27,115) of included patients, with the most common cause of injury being road traffic collisions. A reduction in crude maternal mortality was observed over the course of the study period (7.3% to 2.9%). Baseline mean EQ-5D (0.47) and EQ-VAS (54.08) improved to 0.81 ( < 0.001) and 85.75 ( = 0.001), respectively, at 6 months following injury.

CONCLUSION

The incidence of trauma in pregnancy is small and mortality in injured pregnant women decreased over the study period. Pregnant patients have significantly improved patient-reported outcome measures 6 months after injury although this is limited in impact because of poor response rates and outcome reporting. Construction and validation of tools aiding in outcome reporting will help considerably in understanding further gains in the care of pregnant women.

摘要

引言

创伤占孕妇死亡人数的 20%。创伤后孕妇的受伤特征和结果描述得很差。为了了解和为这一关键受伤人群提供最佳护理,我们使用创伤审核研究网络(TARN)数据库进行了一项研究。

方法

从 TARN 数据库中总共确定了 341 名孕妇和 26774 名 15 至 46 岁的非孕妇女性患者进行比较。比较两组之间的死亡率、横断面成像、血液制品的使用和 EQ-5D 评分。报告了孕妇中创伤网络建立前后的损伤机制、损伤严重程度评分(ISS)和死亡率。

结果

在纳入的患者中,有 1.3%(341/27115)记录了妊娠,受伤的最常见原因是道路交通碰撞。研究期间,产妇死亡率呈下降趋势(7.3%降至 2.9%)。基线平均 EQ-5D(0.47)和 EQ-VAS(54.08)分别改善至 0.81(<0.001)和 85.75(=0.001),在受伤后 6 个月。

结论

妊娠期间创伤的发生率很小,受伤孕妇的死亡率在研究期间有所下降。尽管由于不良的反应率和结果报告,孕妇的患者报告结果指标在 6 个月后有显著改善,但影响有限。构建和验证有助于报告结果的工具将极大地帮助我们了解在孕妇护理方面的进一步进展。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d59/10833001/04b0388218d2/rcsann.2023.0047.01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d59/10833001/04b0388218d2/rcsann.2023.0047.01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d59/10833001/04b0388218d2/rcsann.2023.0047.01.jpg

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