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[左冠状动脉心室微瘘。关于25例]

[Left coronaro-ventricular microfistulas. Apropos of 25 cases].

作者信息

Lefevre T, Haiat R, Guilmet D, Bernard A, Granier J

出版信息

J Radiol. 1986 Apr;67(4):275-83.

PMID:3761236
Abstract

A retrospective study of 25 patients with left coronaroventricular microfistulae, investigated in the same vascular radiologic exploration unit, and data in the international literature were used to analyze these lesions in greater detail. Their frequency appears to have been underestimated since they represented 1.33% of coronarographies performed in adults in this series. Distribution into two groups as a function of presence or absence of significant coronary lesions, vascular disease or myocardial insufficiency showed that the group with isolated microfistulae was composed solely of women of about 50 years of age (16 cases). These patients presented typical angina with a simple course (absence of infarction), but a sometimes severe disability due to the symptomatology. The myocardial ischemia could result from a "coronary steal" phenomenon but other hypotheses have been evoked. Their congenital origin is widely accepted but their relation to atherosclerosis has not been established (cause, consequence or fortuitous association). They present specific images on routine coronarography. Treatment is symptomatic but surgical in exceptional cases with refractory, very disabling angina. Finally, detection of left coronaroventricular microfistulae should, when combined with metabolic studies, allow classification of the difficult problem of "angina with angiographically normal coronary arteries".

摘要

对在同一血管放射学检查单位接受检查的25例左冠状动脉心室微瘘患者进行了回顾性研究,并利用国际文献中的数据对这些病变进行了更详细的分析。由于在该系列成人冠状动脉造影中,它们占1.33%,其发生率似乎被低估了。根据是否存在显著冠状动脉病变、血管疾病或心肌功能不全将患者分为两组,结果显示,孤立性微瘘组仅由约50岁的女性组成(16例)。这些患者表现为典型的心绞痛,病程简单(无梗死),但有时因症状严重而导致残疾。心肌缺血可能是由“冠状动脉窃血”现象引起的,但也有其他假说。它们的先天性起源已被广泛接受,但其与动脉粥样硬化的关系尚未确定(因果关系或偶然关联)。它们在常规冠状动脉造影上呈现出特定的影像。治疗以对症为主,但在极少数难治性、严重致残性心绞痛的情况下需进行手术治疗。最后,左冠状动脉心室微瘘的检测与代谢研究相结合,应有助于对“冠状动脉造影正常的心绞痛”这一难题进行分类。

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