Kaneko M, Takaku I, Katsura N
Jpn J Ophthalmol. 1986;30(2):165-73.
Glycosaminoglycans (GAG) in pterygium tissues were analyzed and the results were compared with those in the normal human conjunctiva. A marked difference in the GAG composition was found: 78% of the total hexosamines of GAG from pterygium was glucosamine, whereas 98% of those of the conjunctiva was galactosamine. Pterygium contained mainly hyaluronic acid (48.8%), followed by chondroitin sulfate A, chondroitin sulfate C, chondroitin and dermatan sulfate in this order. The normal conjunctiva contained mainly chondroitin sulfate C (73.5%), followed by chondroitin sulfate A and chondroitin sulfate E-like GAG. The amino acid composition showed some differences between pterygium and normal conjunctiva. The pterygium tissues contained an extremely large amount of hydroxyproline, but the conjunctiva contained a very small amount of this substance. Considerable changes in amino acid composition of both tissues were found after digestion with elastase.
对翼状胬肉组织中的糖胺聚糖（GAG）进行了分析，并将结果与正常人结膜中的结果进行了比较。发现GAG的组成存在显著差异：翼状胬肉中GAG的总己糖胺的78%是葡萄糖胺，而结膜中这一比例为98%是半乳糖胺。翼状胬肉主要含有透明质酸（48.8%），其次依次为硫酸软骨素A、硫酸软骨素C、软骨素和硫酸皮肤素。正常结膜主要含有硫酸软骨素C（73.5%），其次是硫酸软骨素A和硫酸软骨素E样GAG。氨基酸组成在翼状胬肉和正常结膜之间存在一些差异。翼状胬肉组织中含有极大量的羟脯氨酸，但结膜中这种物质的含量非常少。用弹性蛋白酶消化后，发现两种组织的氨基酸组成都有相当大的变化。
