Pereira Gonçalves Jessica, Briand Madrid Laélia, Donadille Cécile, Michels David, Ahouah Mathieu, Rojas Castro Daniela, Roux Perrine
Aix Marseille Univ, INSERM, IRD, SESSTIM, Sciences Economiques & Sociales de la Santé & Traitement de l'Information Médicale, ISSPAM, Marseille, France.
Laboratoire de recherche communautaire, Coalition PLUS, Pantin, France; AIDES, Pantin, France.
Rev Epidemiol Sante Publique. 2023 Oct;71(5):102142. doi: 10.1016/j.respe.2023.102142. Epub 2023 Aug 23.
Cutaneous abscesses are a common complication of intravenous substance use. Although these skin and soft tissue infections represent one of the main causes of emergency room visits and hospitalizations in people who inject drugs (PWID), data on their prevalence and causes are scarce. The present study was part of the larger ANRS-OUTSIDER project and aimed to study the factors associated with skin abscesses in PWID, focusing in particular on the different stages of injection.
Analyses were based on data of the 164 persons who regularly injected psychoactive substances participating in the French ANRS-OUTSIDER project. A face-to-face questionnaire collected data on sociodemographics, substance use, injection practices, and experience of skin abscesses in the previous six months. Factors associated with skin abscesses were studied using a logistic regression model.
Of the 140 participants for whom abscess data were recorded at inclusion, 35% reported having a skin abscess in the previous six months. Factors associated with skin abscesses were: benefiting from universal health coverage (PUMA/CMU/AME) (Odd ratio (OR) = 0.28, confidence interval (CI) à 95%=0.08-0.99), finding the vein to inject by touch (OR=3.44, 95% CI=1.41-8.43) and licking the needle before injection (OR=5.16, 95% CI=1.10-24.30).
Our results highlight that skin abscesses were very frequent among the complications observed in our sample of French PWID, and that certain injection practices fostered their occurrence. These data will provide stakeholders with useful information to improve prevention and harm reduction messages for PWID.
皮肤脓肿是静脉注射毒品的常见并发症。尽管这些皮肤和软组织感染是注射吸毒者（PWID）急诊就诊和住院的主要原因之一，但关于其患病率和病因的数据却很稀少。本研究是规模更大的法国国家艾滋病研究机构（ANRS）-局外人项目的一部分，旨在研究与注射吸毒者皮肤脓肿相关的因素，尤其关注注射的不同阶段。
分析基于参与法国ANRS-局外人项目的164名定期注射精神活性物质者的数据。通过面对面问卷调查收集社会人口统计学、物质使用、注射行为以及过去六个月皮肤脓肿经历等方面的数据。使用逻辑回归模型研究与皮肤脓肿相关的因素。
在纳入时记录有脓肿数据的140名参与者中，35%报告在过去六个月内有皮肤脓肿。与皮肤脓肿相关的因素有：享受全民医保（PUMA/CMU/AME）（比值比（OR）=0.28，95%置信区间（CI）=0.08 - 0.99）、通过触摸找到注射静脉（OR = 3.44，95% CI = 1.41 - 8.43）以及注射前舔针（OR = 5.16，95% CI = 1.10 - 24.30）。
我们的结果表明，在我们的法国注射吸毒者样本中观察到的并发症中，皮肤脓肿非常常见，并且某些注射行为会促使其发生。这些数据将为利益相关者提供有用信息，以改进针对注射吸毒者的预防和减少伤害信息。
