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[变应性鼻炎氩激光条形炭化后下鼻甲呼吸黏膜上皮的组织学变化]

[Histologic changes in the epithelium of the respiratory mucosa of the lower turbinates following argon laser strip carbonization in vasomotor rhinitis].

作者信息

Lenz H, Preussler H

出版信息

Laryngol Rhinol Otol (Stuttg). 1986 Aug;65(8):438-44.

PMID:3762277
Abstract

The histological findings after argon-ion-laser-carbonization on the respiratory mucosa of the lower turbinates in vasomotor rhinitis are described directly after laser treatment and 6 years later. The laser surgical procedure without bleeding, the reduction of swelling of the lower turbinates, a slight diminishing of secretion, a significantly better nasal ventilation are demonstrated by the histological findings. The main characteristic histological findings are: a cuneiform laser lesion extending deep into the tissue to the venous plexus, four different typical tissue layers immediately after laser treatment, centrally the carbonization zone surrounded by a coagulation zone and next to this a honeycombed zone surrounded by a very small oedematous zone. Healing of the laser lesion is always complete. First of all, a squamous epithelium with subepithelial fibrosis and hypertrophy of the muscle cells in the venous plexus are seen. Half a year after laser carbonization metaplasia of the stratified squamous epithelium into pseudostratified cylindrical ciliated epithelium is seen. Occasionally, small islands of stratified squamous epithelium are visible.

摘要

本文描述了在血管运动性鼻炎患者下鼻甲呼吸黏膜进行氩离子激光碳化治疗后即刻以及6年后的组织学发现。组织学结果显示,激光手术操作无出血,下鼻甲肿胀减轻,分泌物略有减少,鼻腔通气明显改善。主要的组织学特征性发现为:楔形激光损伤深入组织至静脉丛;激光治疗后立即出现四种不同的典型组织层,中央为碳化区,周围是凝固区,再往外是蜂窝状区,其周围为非常小的水肿区。激光损伤总能完全愈合。首先可见鳞状上皮,伴有上皮下纤维化和静脉丛中肌细胞肥大。激光碳化半年后,可见复层鳞状上皮化生为假复层柱状纤毛上皮。偶尔可见复层鳞状上皮小岛。

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