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罕见的伪装成眶下肿物——瑞士一名乌克兰患者眼部感染犬恶丝虫病的病例报告

Unusual Masquerading Infraorbital Mass-A Case Report of Human Ocular Dirofilariosis Found in A Ukrainian Patient in Switzerland.

作者信息

Menna Feliciana, Billia Filippo, Papazoglou Anthia, Tschopp Markus, Grobholz Rainer

机构信息

Department of Ophthalmology, Cantonal Hospital Aarau, CH-5001 Aarau, Switzerland.

Department of Ophthalmology, Inselspital, Bern University Hospital, University of Bern, 3010 Bern, Switzerland.

出版信息

Pathogens. 2023 Jul 27;12(8):982. doi: 10.3390/pathogens12080982.

DOI:10.3390/pathogens12080982
PMID:37623942
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10459646/
Abstract

A 78-year-old Ukrainian woman who had immigrated to Switzerland presented with a rapid growing subcutaneous infraorbital mass. Surgical excision of the mass revealed a well-circumscribed, encapsulated tumor, adherent to the skin. The excision showed a soft tissue inflammation with parts of spp. The number of cases of human dirofilariosis reported in the last 50 years has gradually increased. is now endemic in many countries and is currently considered to be one of the fast spreading zoonoses in Central, Eastern and Northern Europe. The first empirical evidence of Swiss spreading of infections was in a dog from southern Switzerland in 1998. Ours is the first case of human orbital dirofilariosis found in a Ukranian patient reported in Switzerland. Our purpose is to inform the ophthalmologist to consider orbital dirofilariosis in the differential diagnosis of inflammatory masses of the orbit and to warn about the spread of this infection in Switzerland.

摘要

一名移民到瑞士的78岁乌克兰女性出现了快速生长的眶下皮下肿块。对该肿块进行手术切除后发现是一个边界清晰、有包膜的肿瘤,与皮肤粘连。切除显示为软组织炎症,伴有部分 spp。过去50年报告的人体恶丝虫病病例数量逐渐增加。该病目前在许多国家呈地方性流行,目前被认为是中欧、东欧和北欧快速传播的人畜共患病之一。1998年,瑞士南部一只狗身上首次出现了恶丝虫感染在瑞士传播的实证证据。我们的病例是瑞士报告的首例在乌克兰患者中发现的人体眼眶恶丝虫病。我们的目的是告知眼科医生在眼眶炎性肿块的鉴别诊断中考虑眼眶恶丝虫病,并提醒注意这种感染在瑞士的传播情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3cd9/10459646/26f4dcca5bb3/pathogens-12-00982-g003a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3cd9/10459646/6ca851a976d5/pathogens-12-00982-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3cd9/10459646/22b82245ebcc/pathogens-12-00982-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3cd9/10459646/26f4dcca5bb3/pathogens-12-00982-g003a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3cd9/10459646/6ca851a976d5/pathogens-12-00982-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3cd9/10459646/22b82245ebcc/pathogens-12-00982-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3cd9/10459646/26f4dcca5bb3/pathogens-12-00982-g003a.jpg

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本文引用的文献

1
Subcutaneous Dirofilariosis of the Eyelid Brought to Poland from the Endemic Territory of Ukraine.从乌克兰流行地区传入波兰的眼睑皮下丝虫病
Pathogens. 2023 Jan 28;12(2):196. doi: 10.3390/pathogens12020196.
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Orbital Dirofilariasis Masquerading As Orbital Rhabdomyosarcoma.伪装成眼眶横纹肌肉瘤的眼眶丝虫病
J Ophthalmic Vis Res. 2022 Nov 29;17(4):587-591. doi: 10.18502/jovr.v17i4.12340. eCollection 2022 Oct-Dec.
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First case of ocular dirofilariosis in Bulgaria caused by gravid female Dirofilaria repens.保加利亚首例由妊娠雌性犬恶丝虫引起的眼丝虫病。
Ann Parasitol. 2022;68(1):191-193. doi: 10.17420/ap6801.424.
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The emergence of Dirofilaria repens in a non-endemic area influenced by climate change: dynamics of transmission using a mathematical model.在气候变化影响下的非流行地区出现了复孔绦虫:使用数学模型进行传播动态研究。
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Human dirofilariosis in the 21st century: A scoping review of clinical cases reported in the literature.21 世纪的人患犬心丝虫病:文献中报告的临床病例的范围综述。
Transbound Emerg Dis. 2022 Sep;69(5):2424-2439. doi: 10.1111/tbed.14210. Epub 2021 Jul 10.
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Recent advances on Dirofilaria repens in dogs and humans in Europe.欧洲犬和人体内繁殖息丝虫的最新研究进展。
Parasit Vectors. 2018 Dec 19;11(1):663. doi: 10.1186/s13071-018-3205-x.
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Ocular dirofilariasis: a case series of 8 patients.眼盘尾丝虫病:8例病例系列
Middle East Afr J Ophthalmol. 2014 Oct-Dec;21(4):312-6. doi: 10.4103/0974-9233.142267.
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Regional warming and emerging vector-borne zoonotic dirofilariosis in the Russian Federation, Ukraine, and other post-Soviet states from 1981 to 2011 and projection by 2030.1981 年至 2011 年期间俄罗斯联邦、乌克兰和其他前苏联国家的区域变暖与新发媒介传播的血孢子虫病,以及到 2030 年的预测。
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Human dirofilariasis due to Dirofilaria repens in Ukraine, an emergent zoonosis: epidemiological report of 1465 cases.乌克兰因匐行恶丝虫引起的人体恶丝虫病,一种新发人畜共患病:1465例病例的流行病学报告
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