Icahn School of Medicine at Mount Sinai, New York; Division of Pediatric Gastroenterology, Susan and Leonard Feinstein Inflammatory Bowel Disease Center, 17 E 102nd Street, 5th floor east, New York, NY, 10029-5204, USA.
Curr Gastroenterol Rep. 2023 Nov;25(11):355-361. doi: 10.1007/s11894-023-00892-7. Epub 2023 Aug 25.
Intestinal ultrasound (IUS) is an emerging non-invasive point-of-care tool utilized by pediatric gastroenterologists for accurately detecting and monitoring inflammatory bowel disease (IBD) activity. In this article, we reviewed the evidence supporting and technique to perform IUS for children with IBD.
IUS technique can visualize the colon from the distal sigmoid until the cecum and the terminal ileum without the need for bowel preparation, fasting, or sedation in children with IBD. IUS has been shown to be accurate to endoscopy in children with ulcerative colitis and Crohn's disease. IUS may be the most accurate biomarker to follow as a marker of treatment response that is predictive of endoscopic outcomes in children with IBD. Multiple studies have demonstrated that IUS can be performed at the point-of-care for IBD activity assessment in children. Recent studies have demonstrated the accuracy of IUS to endoscopy and magnetic resonance enterography with an ability to be repeated as a monitor of treatment response for tight control monitoring.
肠道超声(IUS)是一种新兴的非侵入性即时检测工具,被儿科胃肠病学家用于准确检测和监测炎症性肠病(IBD)的活动。本文综述了支持 IUS 用于 IBD 患儿的证据和技术。
IUS 技术可在无需肠道准备、禁食或镇静的情况下,从远端乙状结肠可视化到盲肠和末端回肠,在 IBD 患儿中。IUS 已被证明在溃疡性结肠炎和克罗恩病患儿中与内镜检查一样准确。IUS 可能是最准确的生物标志物,可作为治疗反应的标志物,预测 IBD 患儿的内镜结果。多项研究表明,IUS 可在床边进行,用于评估 IBD 患儿的活动。最近的研究表明,IUS 在评估 IBD 活动方面与内镜和磁共振肠造影术具有相同的准确性,并且能够作为紧密控制监测的治疗反应监测手段进行重复。