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肠超声在炎症性肠病中的临床应用。

Clinical Application of Intestinal Ultrasound in Inflammatory Bowel Disease.

机构信息

Inflammatory Bowel Disease Center, University of Chicago, 5841 S. Maryland Ave MC 4076, Chicago, IL, 60637, USA.

出版信息

Curr Gastroenterol Rep. 2024 Feb;26(2):31-40. doi: 10.1007/s11894-024-00915-x. Epub 2024 Jan 20.

Abstract

PURPOSE OF REVIEW

Intestinal ultrasound (IUS) is a non-invasive, accurate, and well-tolerated tool that provides real-time assessment of inflammatory bowel disease (IBD) activity and is therefore an ideal monitoring tool. This review describes the evolving role of IUS in each phase of clinical management of IBD.

RECENT FINDINGS

Accumulating evidence has demonstrated that IUS is an excellent tool for the assessment of suspected IBD, with a very high negative predictive value. It accurately assesses disease activity, disease complications, and in the pre-treatment phase, provides a benchmark for subsequent follow-up. IUS can detect early therapeutic response and correlates well with other established monitoring modalities with arguably superior predictive capabilities and ability to assess a deeper degree of remission, transmural healing (TH). IUS has a crucial role in the management of IBD and has ushered in a new era of monitoring with more rapid evaluation and the opportunity for early optimization, deeper therapeutic targets, and improved outcomes.

摘要

目的综述

肠道超声(IUS)是一种非侵入性、准确且耐受性良好的工具,可实时评估炎症性肠病(IBD)的活动,因此是一种理想的监测工具。本综述描述了 IUS 在 IBD 临床管理的各个阶段不断发展的作用。

最近的发现

越来越多的证据表明,IUS 是评估疑似 IBD 的极好工具,具有非常高的阴性预测值。它可以准确评估疾病活动、疾病并发症,并且在治疗前阶段,为后续随访提供基准。IUS 可以检测早期治疗反应,与其他已建立的监测方式具有良好的相关性,具有更好的预测能力,并能够评估更深程度的缓解、透壁愈合(TH)。IUS 在 IBD 的管理中具有重要作用,开创了监测的新时代,可更快速地评估、有机会早期优化、更深的治疗目标以及改善结果。

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