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肠道超声作为一种非侵入性工具,可用于监测炎症性肠病的活动并指导临床决策。

Intestinal ultrasound as a non-invasive tool to monitor inflammatory bowel disease activity and guide clinical decision making.

机构信息

Department of Pediatric Gastroenterology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States.

Department of Medicine, Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States.

出版信息

World J Gastroenterol. 2023 Apr 21;29(15):2272-2282. doi: 10.3748/wjg.v29.i15.2272.

DOI:10.3748/wjg.v29.i15.2272
PMID:37124889
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10134421/
Abstract

Intestinal ultrasound (IUS) is a non-invasive, real-time, cross-sectional imaging tool that can be used at the point-of-care to assess disease activity in patients with Crohn's disease or ulcerative colitis. IUS promotes quick and impactful treatment decisions that can modify disease progression and enhance patient compliance. This review will summarize the technical aspects of IUS, the evidence to support the use of IUS in disease activity monitoring, the comparison of IUS to current standard of care monitoring modalities such as colonoscopy and calprotectin, and the optimal positioning of IUS in a tight-control monitoring strategy.

摘要

肠超声(IUS)是一种非侵入性、实时的、横断面成像工具,可在床边使用,以评估克罗恩病或溃疡性结肠炎患者的疾病活动度。IUS 可促进快速而有影响力的治疗决策,从而改变疾病进程并提高患者的依从性。本文将总结 IUS 的技术方面、支持 IUS 在疾病活动监测中应用的证据、IUS 与当前标准护理监测方式(如结肠镜检查和钙卫蛋白)的比较,以及 IUS 在严格控制监测策略中的最佳定位。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/993c/10134421/32c589c4bba3/WJG-29-2272-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/993c/10134421/af4a795d9061/WJG-29-2272-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/993c/10134421/aab450b7113d/WJG-29-2272-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/993c/10134421/83376d6396ba/WJG-29-2272-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/993c/10134421/32c589c4bba3/WJG-29-2272-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/993c/10134421/af4a795d9061/WJG-29-2272-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/993c/10134421/aab450b7113d/WJG-29-2272-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/993c/10134421/83376d6396ba/WJG-29-2272-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/993c/10134421/32c589c4bba3/WJG-29-2272-g004.jpg

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Gastroenterology. 2022 Dec;163(6):1569-1581. doi: 10.1053/j.gastro.2022.08.038. Epub 2022 Aug 24.
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Early Ultrasound Response and Progressive Transmural Remission After Treatment With Ustekinumab in Crohn's Disease.克罗恩病患者使用优特克单抗治疗后的早期超声反应及透壁缓解进展
Clin Gastroenterol Hepatol. 2023 Jan;21(1):153-163.e12. doi: 10.1016/j.cgh.2022.05.055. Epub 2022 Jul 14.
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Curr Gastroenterol Rep. 2025 Aug 12;27(1):61. doi: 10.1007/s11894-025-01010-5.
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J Clin Med. 2025 Jul 8;14(14):4817. doi: 10.3390/jcm14144817.
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Correlation between intestinal ultrasound and fecal calprotectin with endoscopic severity scores for determining the activity in patients with Crohn's disease.肠道超声及粪便钙卫蛋白与内镜严重程度评分在确定克罗恩病患者疾病活动度中的相关性
Abdom Radiol (NY). 2025 Jul 9. doi: 10.1007/s00261-025-05099-0.
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