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前庭神经鞘瘤显微手术后长期术后头痛相关的病前心理因素——一项回顾性初步研究

Premorbid Psychological Factors Associated with Long-Term Postoperative Headache after Microsurgery in Vestibular Schwannoma-A Retrospective Pilot Study.

作者信息

Thomas Mareike, Rampp Stefan, Scheer Maximilian, Strauss Christian, Prell Julian, Schönfeld Robby, Leplow Bernd

机构信息

Department of Medical Psychology, Center for Psychosocial Medicine, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.

Department of Psychology, Martin-Luther-Universität Halle-Wittenberg, Emil-Abderhalden-Straße 26-27, 06108 Halle, Germany.

出版信息

Brain Sci. 2023 Aug 7;13(8):1171. doi: 10.3390/brainsci13081171.

Abstract

Associations between premorbid psychological factors and postoperative headache (POH) after microsurgical treatment via the retrosigmoid approach for vestibular schwannoma (VS) were investigated in this retrospective single-center study. A total of 101 VS patients completed the Rostock headache questionnaire (RoKoKo), the hospital and anxiety scale (HADS-D), and the screening for somatoform disorders (SOMS-2), all of which were used as short self-assessed questionnaires. Fifty-four patients with POH were compared with 47 non-POH patients in terms of premorbid psychological factors, somatization tendencies, and psychological burden using the chi-test and Mann-Whitney -test. Regression analyses were conducted to assess the weighted contribution of psychological and procedural factors to POH. In individuals with POH, mental ailments, preexisting headaches, premorbid chronic pain syndromes, and higher somatization tendencies were found to be significantly more common. POH was predicted by the number of premorbid psychosomatic symptoms, preexisting mental ailments, and premorbid chronic pain syndromes. Depression and anxiety were predicted by low emotional stability. Additionally, the number of premorbid psychosomatic symptoms predicted depression, anxiety, and overall psychological burden. It was observed that the reported symptoms of headache might fit into the classification of chronic postsurgical pain (CPSP) rather than being classified as secondary headaches after craniotomy. Premorbid psychological factors were found to play an important role in the emergence of POH in VS, particularly after microsurgery via the retrosigmoid approach. Therefore, it is suggested that psychological screening be incorporated into the treatment process.

摘要

在这项回顾性单中心研究中,我们调查了通过乙状窦后入路显微手术治疗前庭神经鞘瘤(VS)前的心理因素与术后头痛(POH)之间的关联。共有101例VS患者完成了罗斯托克头痛问卷(RoKoKo)、医院焦虑量表(HADS-D)和躯体形式障碍筛查(SOMS-2),所有这些都用作简短的自我评估问卷。使用卡方检验和曼-惠特尼检验,比较了54例POH患者和47例非POH患者在病前心理因素、躯体化倾向和心理负担方面的差异。进行回归分析以评估心理因素和手术因素对POH的加权贡献。在POH患者中,发现精神疾病、既往头痛、病前慢性疼痛综合征和更高的躯体化倾向明显更为常见。POH可通过病前心身症状的数量、既往精神疾病和病前慢性疼痛综合征来预测。情绪稳定性低可预测抑郁和焦虑。此外,病前心身症状的数量可预测抑郁、焦虑和总体心理负担。据观察,报告的头痛症状可能符合慢性术后疼痛(CPSP)的分类,而不是被归类为开颅术后的继发性头痛。发现病前心理因素在VS患者POH的发生中起重要作用,尤其是在通过乙状窦后入路进行显微手术后。因此,建议将心理筛查纳入治疗过程。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/032b/10452443/6e4a0b5df533/brainsci-13-01171-g001.jpg

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