Raicu Anca-Maria, Danila George-Florin, Secheli Ionut Fernando, Bratu Eugenia Claudia, Minca Dana Galieta
Department of Public Health and Management, "Carol Davila" University of Medicine and Pharmacy, 050463 Bucharest, Romania.
Department of Paediatric Surgery, Emergency Hospital for Children "M.S.Curie", 041451 Bucharest, Romania.
Children (Basel). 2023 Jul 30;10(8):1314. doi: 10.3390/children10081314.
Infantile haemangioma (IH) is the most common benign tumour in childhood, with an incidence of 4% to 12%. Aim: to describe the characteristics of infantile haemangioma in a sample of Romanian children <2 years old at diagnosis, types of treatment applied, recorded complications and the response to the therapeutic approach. A two-year prospective case series study (August 2019 to August 2021) was carried out. Sample: 117 patients <24 months of age diagnosed with IH at the Emergency Hospital for Children "Marie Sklodowska Curie", in Bucharest, Romania. Five therapeutic approaches were used: oral treatment with propranolol, local treatment with timolol, surgical treatment, topical treatment with steroids and no treatment ("wait and see"). Recorded factors mentioned in the literature were also present in this study population: female patients-68.4%; phototype I-58%. In 53% of cases, IHs had a head and neck location and 10% developed local complications (traumatic bleeding). The majority of patients (86%) required one type of therapy: oral propranolol (51%). A low relapse rate was recorded (4%). We consider that any child with a vascular anomaly should be referred to a highly specialised medical service for therapeutic approach.
婴儿血管瘤（IH）是儿童期最常见的良性肿瘤，发病率为4%至12%。目的：描述罗马尼亚2岁以下确诊儿童样本中婴儿血管瘤的特征、所采用的治疗类型、记录的并发症以及对治疗方法的反应。开展了一项为期两年的前瞻性病例系列研究（2019年8月至2021年8月）。样本：罗马尼亚布加勒斯特“玛丽·居里”儿童医院急诊科诊断为IH的117例24个月以下患者。采用了五种治疗方法：普萘洛尔口服治疗、噻吗洛尔局部治疗、手术治疗、类固醇局部治疗和不治疗（“观察等待”）。本研究人群中也存在文献中提到的记录因素：女性患者占68.4%；I型肤色占58%。53%的病例中，婴儿血管瘤位于头颈部，10%出现局部并发症（创伤性出血）。大多数患者（86%）需要一种治疗方法：口服普萘洛尔（51%）。记录的复发率较低（4%）。我们认为，任何患有血管异常的儿童都应转诊至高度专业化的医疗服务机构进行治疗。
