Popović Milka B, Medić Deana D, Velicki Radmila S, Jovanović Galović Aleksandra I
Department of Hygiene, Faculty of Medicine, University of Novi Sad, Hajduk Veljkova 3, 21000 Novi Sad, Serbia.
Center for Hygiene and Human Ecology, Institute of Public Health of Vojvodina, Futoška 121, 21000 Novi Sad, Serbia.
Healthcare (Basel). 2023 Aug 10;11(16):2251. doi: 10.3390/healthcare11162251.
Purple urine bag syndrome (PUBS) is an uncommon, but usually benign, underrecognized clinical condition with the distressing presentation of purple, blue or reddish discoloration of a patient's catheter bag and tubing in the setting of catheter-associated urinary tract infections (UTIs). PUBS is the result of the complex metabolic pathway of the dietary essential amino acid tryptophan. Its urinary metabolite, indoxyl sulfate, is converted into red and blue byproducts (indirubin and indigo) in the presence of the bacterial enzymes indoxyl sulfatase and phosphatase. The typical predisposing factors are numerous and include the following: female gender, advanced age, long-term catheterization and immobilization, constipation, institutionalization, dementia, increased dietary intake of tryptophan, chronic kidney disease, alkaline urine, and spinal cord injury (SCI). Here, we present a case of PUBS in a home-dwelling elderly female patient with a history of long-term immobility after a pathological spinal fracture, long-term catheterization, constipation, and malignant disease in remission. Urine culture was positive for . This state can be alarming to both patients and physicians, even if the patient is asymptomatic. Healthcare professionals and caregivers need to be aware of this unusual syndrome as an indicator of bacteriuria in order to initiate proper diagnostics and treatment.
紫色尿袋综合征（PUBS）是一种罕见但通常为良性的、未被充分认识的临床病症，在与导尿管相关的尿路感染（UTIs）情况下，患者的导尿管袋和管道会出现令人苦恼的紫色、蓝色或红色变色。PUBS是饮食必需氨基酸色氨酸复杂代谢途径的结果。其尿液代谢产物硫酸吲哚酚在细菌酶吲哚酚硫酸酯酶和磷酸酶的作用下转化为红色和蓝色副产物（靛玉红和靛蓝）。典型的诱发因素众多，包括：女性、高龄、长期导尿和固定不动、便秘、住院、痴呆、色氨酸饮食摄入量增加、慢性肾病、碱性尿液和脊髓损伤（SCI）。在此，我们报告一例居家老年女性患者的PUBS病例，该患者有病理性脊柱骨折后长期卧床、长期导尿、便秘病史，恶性疾病处于缓解期。尿培养结果为 阳性。这种情况可能会让患者和医生都感到担忧，即使患者没有症状。医护人员和护理人员需要了解这种不寻常的综合征，将其作为菌尿的一个指标，以便启动适当的诊断和治疗。
