Barakat Rubén, Zhang Dingfeng, Silva-José Cristina, Sánchez-Polán Miguel, Franco Evelia, Mottola Michelle F
AFIPE Research Group, Faculty of Physical Activity and Sport Sciences-INEF, Universidad Politécnica de Madrid, 28040 Madrid, Spain.
Department of Education, Research and Evaluation Methods, Faculty of Social and Human Sciences, Universidad Pontificia de Comillas, 28049 Madrid, Spain.
J Clin Med. 2023 Aug 19;12(16):5393. doi: 10.3390/jcm12165393.
Miscarriage is an inability to complete the normal process of pregnancy and childbirth and represents a major concern for pregnant women that can be an emotionally devastating event. While it has been suggested that engaging in strenuous physical activity might be associated with an elevated risk of miscarriage, there is a recent systematic review that suggested that prenatal exercise is not associated with fetal mortality. The aim of this systematic review and meta-analysis (SR + MA) was to assess the effects of physical activity during pregnancy on the likelihood of experiencing a miscarriage (Registration No.: CRD42022370629). Thirteen randomized clinical trials (3728 pregnant women) were included. Meta-analyses were conducted with the dependent variable being the miscarriage ratio in each study. The total risk ratio (RR) sum was calculated using a random effects model. The I statistic was utilized to quantify the heterogeneity observed in the results. No significant association between exercise during pregnancy and the occurrence of miscarriage was found (RR = 0.83 95% CI = 0.83 (0.49-1.41); z = 0.69, = 0.49; I = 0.00%, Heterogeneity = 0.91). Results of the present SR + MA showed no increase in miscarriage risk in those who engaged in low- to moderate-intensity exercise compared to those who did not.
流产是指无法完成正常的妊娠和分娩过程，这是孕妇主要关注的问题，可能会造成情感上的毁灭性打击。虽然有人认为剧烈运动可能会增加流产风险，但最近一项系统评价表明，孕期运动与胎儿死亡率无关。本系统评价和荟萃分析（SR+MA）的目的是评估孕期体育活动对流产可能性的影响（注册号：CRD42022370629）。纳入了13项随机临床试验（3728名孕妇）。以各研究中的流产率作为因变量进行荟萃分析。使用随机效应模型计算总风险比（RR）总和。I统计量用于量化结果中观察到的异质性。未发现孕期运动与流产发生之间存在显著关联（RR=0.83，95%CI=0.83（0.49-1.41）；z=0.69，P=0.49；I²=0.00%，异质性检验P=0.91）。本SR+MA的结果显示，与未进行运动的人相比，进行低至中等强度运动的人流产风险没有增加。
