Sport and Physical Activity Research Centre, Faculty of Education, Health and Wellbeing, University of Wolverhampton, Wolverhampton WV1 1LY, UK.
Department of Physical Education and Sport Science, University of Thessaly, 421 00 Trikala, Greece.
Medicina (Kaunas). 2023 Aug 1;59(8):1408. doi: 10.3390/medicina59081408.
The aim of the present study is to examine the acute effects of a specially designed musicokinetic (MSK) program for patients with Parkinson's disease (PD) on (a) anxiety levels, (b) select kinematic and kinetic parameters, and (c) frontal cortex hemodynamic responses, during gait initiation and steady-state walking. : This is a blind cross-over randomized control trial (RCT) in which 13 volunteers with PD will attend a 45 min MSK program under the following conditions: (a) a synchronous learning format and (b) an asynchronous remote video-based format. Changes in gait biomechanics and frontal cortex hemodynamic responses will be examined using a 10-camera 3D motion analysis (Vicon T-series, Oxford, UK), and a functional near-infrared spectroscopy (f-NIRS-Portalite, Artinis NL) system, respectively, while anxiety levels will be evaluated using the Hamilton Anxiety Rating Scale. : Guided by the rules of music, where periodicity is distinct, our specially designed MSK program may eventually be beneficial in improving motor difficulties and, hence, reducing anxiety. The combined implementation of f-NIRS in parallel with 3D gait analysis has yet to be evaluated in Parkinsonian patients following a MSK intervention. It is expected that the aforementioned intervention, through better rhythmicity, may improve the automatization of motor control, gait kinematics, and kinetics-supported by decreased frontal cortex hemodynamic activity-which may be linked to reduced anxiety levels.
本研究旨在探讨一种专门设计的音乐运动学（MSK）方案对帕金森病（PD）患者在步态启动和稳态行走期间的（a）焦虑水平、（b）选择运动学和动力学参数和（c）额皮质血流动力学反应的急性影响。这是一项盲法交叉随机对照试验（RCT），其中 13 名 PD 志愿者将参加以下条件下的 45 分钟 MSK 方案：（a）同步学习格式和（b）异步远程视频基础格式。步态生物力学和额皮质血流动力学反应的变化将分别使用 10 个摄像机 3D 运动分析（Vicon T 系列，英国牛津）和功能近红外光谱（f-NIRS-Portalite，Artinis NL）系统进行检查，而焦虑水平将使用汉密尔顿焦虑评定量表进行评估。在音乐的规则指导下，周期性是明显的，我们专门设计的 MSK 方案最终可能有助于改善运动困难，从而降低焦虑。在帕金森病患者接受 MSK 干预后，f-NIRS 与 3D 步态分析的联合实施尚未得到评估。预计，通过更好的节奏性，上述干预措施可能会改善运动控制、步态运动学和动力学的自动化，这可能与降低焦虑水平有关，因为额皮质血流动力学活动减少。
