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由心肌细胞驱动的生物杂交软机器人:当前进展与未来展望

Biohybrid Soft Robots Powered by Myocyte: Current Progress and Future Perspectives.

作者信息

Yuan Zheng, Guo Qinghao, Jin Delu, Zhang Peifan, Yang Wenguang

机构信息

School of Electromechanical and Automotive Engineering, Yantai University, Yantai 264005, China.

School of Human Ities and Social Science, Xi'an Jiaotong University, Xi'an 710049, China.

出版信息

Micromachines (Basel). 2023 Aug 20;14(8):1643. doi: 10.3390/mi14081643.

DOI:10.3390/mi14081643
PMID:37630179
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10456826/
Abstract

Myocyte-driven robots, a type of biological actuator that combines myocytes with abiotic systems, have gained significant attention due to their high energy efficiency, sensitivity, biocompatibility, and self-healing capabilities. These robots have a unique advantage in simulating the structure and function of human tissues and organs. This review covers the research progress in this field, detailing the benefits of myocyte-driven robots over traditional methods, the materials used in their fabrication (including myocytes and extracellular materials), and their properties and manufacturing techniques. Additionally, the review explores various control methods, robot structures, and motion types. Lastly, the potential applications and key challenges faced by myocyte-driven robots are discussed and summarized.

摘要

心肌细胞驱动的机器人是一种将心肌细胞与非生物系统相结合的生物致动器,因其高能量效率、敏感性、生物相容性和自我修复能力而备受关注。这些机器人在模拟人体组织和器官的结构与功能方面具有独特优势。本文综述了该领域的研究进展,详细阐述了心肌细胞驱动的机器人相对于传统方法的优势、制造过程中使用的材料(包括心肌细胞和细胞外材料)及其特性和制造技术。此外,还探讨了各种控制方法、机器人结构和运动类型。最后,讨论并总结了心肌细胞驱动的机器人的潜在应用和面临的关键挑战。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1b3/10456826/7df7c6c7d5fa/micromachines-14-01643-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1b3/10456826/ce4ffb4b5440/micromachines-14-01643-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1b3/10456826/268bd6860607/micromachines-14-01643-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1b3/10456826/2748025d3917/micromachines-14-01643-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1b3/10456826/335ffe0f40bb/micromachines-14-01643-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1b3/10456826/f54606e1ccdc/micromachines-14-01643-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1b3/10456826/c888e65cf567/micromachines-14-01643-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1b3/10456826/37a7436975ab/micromachines-14-01643-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1b3/10456826/54827f46562c/micromachines-14-01643-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1b3/10456826/20d66001a92c/micromachines-14-01643-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1b3/10456826/7df7c6c7d5fa/micromachines-14-01643-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1b3/10456826/ce4ffb4b5440/micromachines-14-01643-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1b3/10456826/268bd6860607/micromachines-14-01643-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1b3/10456826/2748025d3917/micromachines-14-01643-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1b3/10456826/335ffe0f40bb/micromachines-14-01643-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1b3/10456826/f54606e1ccdc/micromachines-14-01643-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1b3/10456826/c888e65cf567/micromachines-14-01643-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1b3/10456826/37a7436975ab/micromachines-14-01643-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1b3/10456826/54827f46562c/micromachines-14-01643-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1b3/10456826/20d66001a92c/micromachines-14-01643-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1b3/10456826/7df7c6c7d5fa/micromachines-14-01643-g010.jpg

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