Cedrone Fabrizio, Montagna Vincenzo, Del Duca Livio, Camplone Laura, Mazzocca Riccardo, Carfagnini Federica, Fortunato Valterio, Di Martino Giuseppe
Hospital Healthcare Management, Local Health Autority of Pescara, Via Renato Paolini, 65124 Pescara, Italy.
Postgraduate School of Hygiene and Preventive Medicine, Università Politecnica delle Marche, 60100 Ancona, Italy.
Vaccines (Basel). 2023 Aug 4;11(8):1324. doi: 10.3390/vaccines11081324.
(SP) has high worldwide incidence and related morbidity and mortality, particularly among children and geriatric patients. SP infection could manifest with pneumonia, bacteremia, sepsis, meningitis, and osteomyelitis. This was a retrospective study aimed at evaluating the incidence, comorbidities, and factors associated with in-hospital mortality of pneumococcal disease-related hospitalization in a province in southern Italy from the years 2015 to 2022. This study was performed in the Local Health Authority (LHA) of Pescara. Data were collected from hospital discharge records (HDRs): this database is composed of 288,110 discharge records from LHA Pescara's hospitals from 2015 to 2022. -related hospitalizations were about 5% of the hospitalizations; 67% of these were without comorbidities; 21% were with one comorbidity; and 13% were with two or more comorbidities. Regarding mortality of SP infection, the most affected age group was older people, with the percentage of cases among the over-65s being more than 50% compared to the other age groups. HDRs represent a valid and useful epidemiological tool for evaluating the direct impact of pneumococcal disease on the population and also indirectly for evaluating the effectiveness of vaccination strategies and directing them.
肺炎球菌（SP）在全球发病率较高，且伴有相关的发病率和死亡率，在儿童和老年患者中尤为明显。SP感染可表现为肺炎、菌血症、败血症、脑膜炎和骨髓炎。这是一项回顾性研究，旨在评估2015年至2022年意大利南部某省肺炎球菌疾病相关住院的发病率、合并症以及与院内死亡率相关的因素。本研究在佩斯卡拉地方卫生当局（LHA）进行。数据从医院出院记录（HDRs）中收集：该数据库由2015年至2022年佩斯卡拉LHA医院的288,110份出院记录组成。与肺炎球菌相关的住院约占住院总数的5%；其中67%无合并症；21%有1种合并症；13%有2种或更多合并症。关于SP感染的死亡率，受影响最大的年龄组是老年人，65岁以上人群中的病例百分比与其他年龄组相比超过50%。HDRs是一种有效的流行病学工具，可用于评估肺炎球菌疾病对人群的直接影响，也可间接评估疫苗接种策略的有效性并指导这些策略。
