游泳者使用无机和有机防晒霜的防晒指数30持久性比较：双盲随机临床试验
The Comparison of Sun Protection Factor 30 Persistence Between Inorganic and Organic Sunscreen in Swimmers: Double-blind Randomized Clinical Trial.
作者信息
Rachmani Karin, Yusharyahya Shannaz Nadia, Sampurna Adhimukti, Ranakusuma Respati W, Widaty Sandra
机构信息
Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo General Hospital, Jakarta, Indonesia.
Clinical Epidemiology and Evidence-Based Medicine Unit, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo General Hospital, Jakarta, Indonesia.
出版信息
JMIR Dermatol. 2023 Jan 4;6:e41633. doi: 10.2196/41633.
BACKGROUND
Long-term sun exposure is one of the risks faced by outdoor swimmers and can cause sunburn. Using sunscreen is one way to prevent sunburn; however, physical activity can trigger sweat, friction, and water washing that can interfere with sunscreen efficacy and decrease its sun protection factor (SPF). Sunscreens are classified into inorganic and organic based on their filter. Organic sunscreen has a better bond to the skin than inorganic sunscreen, which forms a barrier above the skin layer that makes removing it easier. Organic sunscreen lasts longer than inorganic sunscreen when used in physical activities, but it has a limited spectrum, is more photolabile, and is more allergenic.
OBJECTIVE
This study aims to evaluate the persistency of SPF 30 between inorganic and organic sunscreens on the back area after 1.5 hours of swimming.
METHODS
This study is a randomized, split-body, double-blind clinical trial to evaluate the persistency of SPF 30 of the inorganic versus organic sunscreens in swimmers. Randomization was done to allocate the participants into treatment groups. Each participant received inorganic and organic sunscreen treatments applied to the back area. The research participants were swimmers from the Cikini swimming pool and Bina Taruna swimming pool, both in Jakarta, Indonesia.
RESULTS
A total of 22 swimmers were enrolled in this study. The analysis showed no significant difference between the SPF of the two sunscreens before swimming (P=.22). After swimming, the SPF levels of both sunscreens decreased: the inorganic sunscreen decreased from a median of 27 (range 23-47) to 12.3 (range 8-19), and the organic sunscreen decreased from a median of 30 (range 24-47) to 9.9 (range 6-19), which was statistically significant (P<.001). When comparing the SPF of inorganic and organic sunscreens after swimming, there was a statistically significant difference in the decrease in SPF levels between the two groups (P=.02), which indicated a better SPF persistence for inorganic sunscreens when compared to organic sunscreens.
CONCLUSIONS
There was a decrease in the SPF levels of inorganic and organic sunscreens after 1.5 hours of swimming, with better persistence in inorganic sunscreens compared to organic sunscreens.
TRIAL REGISTRATION
ClinicalTrials.gov NCT04618536; https://clinicaltrials.gov/ct2/show/NCT04618536.
INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): RR2-10.2196/42504.
背景
长期暴露在阳光下是户外游泳者面临的风险之一，可能导致晒伤。使用防晒霜是预防晒伤的一种方法；然而，体育活动会引发出汗、摩擦和水洗，这些会干扰防晒霜的功效并降低其防晒系数（SPF）。防晒霜根据其过滤剂可分为无机和有机两类。有机防晒霜与皮肤的结合比无机防晒霜更好，无机防晒霜在皮肤层上方形成一层屏障，使其更容易被去除。在体育活动中使用时，有机防晒霜比无机防晒霜持续时间更长，但它的光谱有限，更易光解，且更具致敏性。
目的
本研究旨在评估游泳1.5小时后，无机和有机防晒霜在背部区域的SPF 30的持久性。
方法
本研究是一项随机、分体、双盲临床试验，旨在评估游泳者中无机与有机防晒霜的SPF 30的持久性。通过随机分组将参与者分配到治疗组。每位参与者在背部区域接受无机和有机防晒霜治疗。研究参与者是来自印度尼西亚雅加达芝基尼游泳池和比纳塔鲁纳游泳池的游泳者。
结果
本研究共招募了22名游泳者。分析显示，游泳前两种防晒霜的SPF之间无显著差异（P = 0.22）。游泳后，两种防晒霜的SPF水平均下降：无机防晒霜的中位数从27（范围23 - 47）降至12.3（范围8 - 19），有机防晒霜的中位数从30（范围24 - 47）降至9.9（范围6 - 19），差异具有统计学意义（P < 0.001）。比较游泳后无机和有机防晒霜的SPF时，两组之间的SPF水平下降存在统计学显著差异（P = 0.02），这表明与有机防晒霜相比，无机防晒霜的SPF持久性更好。
结论
游泳1.5小时后，无机和有机防晒霜的SPF水平均下降，无机防晒霜的持久性优于有机防晒霜。
试验注册
ClinicalTrials.gov NCT04618536；https://clinicaltrials.gov/ct2/show/NCT04618536。
国际注册报告标识符（IRRID）：RR2 - 10.2196/42504。
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