Hu Cong, Feng Jianan, Cao Yiqing, Chen Lizhu, Li Yan
Department of Pharmaceutical Analysis, School of Pharmacy, Fudan University, Shanghai, 201203, China.
Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China; Department of Pharmacy, Tongji Hospital, Tongji University School of Medicine, Shanghai, 200065, China.
Talanta. 2024 Jan 1;266(Pt 2):125092. doi: 10.1016/j.talanta.2023.125092. Epub 2023 Aug 20.
This review summarizes recent advances of deep eutectic solvents (DESs) in sample preparation and determination methods of pesticides in food, environmental, and biological matrices since 2019. Emphasis is placed on new DES categories and emerging microextraction techniques. The former incorporate hydrophobic deep eutectic solvents, magnetic deep eutectic solvents, and responsive switchable deep eutectic solvents, while the latter mainly include dispersive liquid-liquid microextraction, liquid-liquid microextraction based on in-situ formation/decomposition of DESs, single drop microextraction, hollow fiber-liquid phase microextraction, and solid-phase microextraction. The principles, applications, advantages, and limitations of these microextraction techniques are presented. Besides, the use of DESs in chromatographic separation, electrochemical biosensors, fluorescent sensors, and surface-enhanced Raman spectroscopy are discussed. This review is expected to provide a valuable reference for extracting and detecting pesticides or other hazardous contaminants in the future.
本文综述了自2019年以来深共熔溶剂（DESs）在食品、环境和生物基质中农药样品前处理及测定方法方面的最新进展。重点介绍了新型DES类别和新兴的微萃取技术。前者包括疏水型深共熔溶剂、磁性深共熔溶剂和响应型可切换深共熔溶剂，而后者主要包括分散液液微萃取、基于DESs原位形成/分解的液液微萃取、单滴微萃取、中空纤维液相微萃取和固相微萃取。介绍了这些微萃取技术的原理、应用、优点和局限性。此外，还讨论了DESs在色谱分离、电化学生物传感器、荧光传感器和表面增强拉曼光谱中的应用。期望本文综述能为未来农药或其他有害污染物的提取和检测提供有价值的参考。
