Beño-Ruiz-de-la-Sierra Rosa M, Arjona-Valladares Antonio, Fondevila Estevez Sabela, Fernández-Linsenbarth Inés, Díez Álvaro, Molina Vicente
Department of Psychiatry, School of Medicine, University of Valladolid, Valladolid, Spain.
UCM-ISCIII Center for Human Evolution and Behaviour, Madrid, Spain.
Eur J Neurosci. 2023 Oct;58(7):3705-3713. doi: 10.1111/ejn.16125. Epub 2023 Aug 27.
As we speak, corollary discharge mechanisms suppress the auditory conscious perception of the self-generated voice in healthy subjects. This suppression has been associated with the attenuation of the auditory N1 component. To analyse this corollary discharge phenomenon (agency and ownership), we registered the event-related potentials of 42 healthy subjects. The N1 and P2 components were elicited by spoken vowels (talk condition; agency), by played-back vowels recorded with their own voice (listen-self condition; ownership) and by played-back vowels recorded with an external voice (listen-other condition). The N1 amplitude elicited by the talk condition was smaller compared with the listen-self and listen-other conditions. There were no amplitude differences in N1 between listen-self and listen-other conditions. The P2 component did not show differences between conditions. Additionally, a peak latency analysis of N1 and P2 components between the three conditions showed no differences. These findings corroborate previous results showing that the corollary discharge mechanisms dampen sensory responses to self-generated speech (agency experience) and provide new neurophysiological evidence about the similarities in the processing of played-back vowels with our own voice (ownership experience) and with an external voice.
在我们说话时，伴随放电机制会抑制健康受试者对自身发出声音的听觉意识感知。这种抑制与听觉N1成分的衰减有关。为了分析这种伴随放电现象（自主性和自我归属），我们记录了42名健康受试者的事件相关电位。N1和P2成分由说出的元音引发（说话条件；自主性）、由用他们自己的声音录制并回放的元音引发（自我聆听条件；自我归属）以及由用外部声音录制并回放的元音引发（他人聆听条件）。与自我聆听和他人聆听条件相比，说话条件引发的N1波幅较小。自我聆听和他人聆听条件之间的N1波幅没有差异。P2成分在各条件之间未显示出差异。此外，对三种条件下N1和P2成分的峰潜伏期分析也未显示出差异。这些发现证实了先前的结果，即伴随放电机制会减弱对自身发出语音的感觉反应（自主性体验），并为用我们自己的声音（自我归属体验）和用外部声音回放元音的处理过程中的相似性提供了新的神经生理学证据。
