年龄和甲状腺激素作为BHE大鼠对饥饿-再喂养反应的因素。
Age and thyroid hormone as factors in the responses of BHE rats to starvation-refeeding.
作者信息
Kim M J, Pan J S, Berdanier C D
出版信息
Proc Soc Exp Biol Med. 1986 Nov;183(2):273-8. doi: 10.3181/00379727-183-42418.
The interacting effects of thyroid hormone, age, and duration of starvation on the enzyme and liver lipid responses of BHE rats to starvation-refeeding were studied. Rats were starved for 2, 4, or 7 days and refed a 65% glucose diet for 2 days. The rats were either 150 or 420 days of age and injected daily with either saline or 10 micrograms thyroxine/100 g body weight. Neither age nor duration of starvation affected the glucose-6-phosphate dehydrogenase or malic enzyme activity or liver lipid response to starvation-refeeding. However, thyroxine treatment potentiated the response to starvation-refeeding in the 420-day-old rats when the duration of starvation increased from 2 to 7 days.
研究了甲状腺激素、年龄和饥饿持续时间对BHE大鼠饥饿-再喂养时酶和肝脏脂质反应的相互作用。大鼠饥饿2、4或7天，然后再喂65%葡萄糖饮食2天。大鼠年龄为150天或420天，每天注射生理盐水或10微克甲状腺素/100克体重。年龄和饥饿持续时间均不影响葡萄糖-6-磷酸脱氢酶或苹果酸酶活性以及肝脏脂质对饥饿-再喂养的反应。然而，当饥饿持续时间从2天增加到7天时，甲状腺素处理增强了420日龄大鼠对饥饿-再喂养的反应。
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