Song Jingjing, Gao Yuyan, Wang Yufei, Dai Huan, Jia Xiaoxiao, Xiang Qiangwei, Zhang Hui, Zheng Rongying, Zhang Weixi
Department of Pediatric Allergy and Immunology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, 325027, People's Republic of China.
J Asthma Allergy. 2023 Aug 22;16:879-887. doi: 10.2147/JAA.S422534. eCollection 2023.
To compare the anxiety, depression and sleep quality of mothers of healthy control children and mothers of children with atopic dermatitis (AD) of varying severity, both before and after treatment.
A total of 120 parent-child dyads participated in the study. These dyads were divided into four subgroups of 30 patients each: mild AD, moderate AD, severe AD, and control groups. The children's symptoms, their mothers' psychological status, and their mothers' sleep quality were evaluated using the Scoring of Atopic Dermatitis (SCORAD), the Hospital Anxiety and Depression Scale (HADS), and the Pittsburgh Sleep Quality Index (PSQI), respectively, before and after a one-month comprehensive treatment.
SCORAD, representing differences in severity of children's AD, decreased significantly after one month's treatment ( < 0.001). Anxiety in mothers significantly decreased in all AD severity groups after treatment ( < 0.05). However, for depression, only the mothers in the mild and moderate AD groups showed a decrease after treatment ( < 0.05). The PSQI total score also decreased in the mild AD group after treatment ( < 0.05).
The most severe effect was seen in the psychology and sleep quality of mothers of children with severe AD. After one month of treatment, the psychological health and sleep quality of the mothers in the mild AD group significantly improved, while those of mothers in the moderate and severe AD groups showed partial improvement.
比较健康对照儿童的母亲与不同严重程度特应性皮炎（AD）患儿的母亲在治疗前后的焦虑、抑郁和睡眠质量。
共有120对亲子参与了该研究。这些亲子被分为四个亚组，每组30例患者：轻度AD组、中度AD组、重度AD组和对照组。在为期一个月的综合治疗前后，分别使用特应性皮炎评分（SCORAD）、医院焦虑抑郁量表（HADS）和匹兹堡睡眠质量指数（PSQI）对儿童症状、母亲的心理状态和母亲的睡眠质量进行评估。
代表儿童AD严重程度差异的SCORAD在治疗一个月后显著降低（<0.001）。治疗后，所有AD严重程度组母亲的焦虑均显著降低（<0.05）。然而，对于抑郁，只有轻度和中度AD组的母亲在治疗后有所降低（<0.05）。治疗后轻度AD组的PSQI总分也有所降低（<0.05）。
重度AD患儿母亲的心理和睡眠质量受影响最为严重。治疗一个月后，轻度AD组母亲的心理健康和睡眠质量显著改善，而中度和重度AD组母亲的心理健康和睡眠质量则有部分改善。
