John Sealy School of Medicine, University of Texas Medical Branch. Galveston, TX, USA.
Department of Population Health and Health Disparities. School of Public and Population Health, University of Texas Medical Branch, Galveston, TX, USA.
J Alzheimers Dis. 2023;95(3):1029-1039. doi: 10.3233/JAD-230286.
The prevalence of type 2 diabetes in Mexico has nearly doubled for adults aged ≥60. Increases in education and healthcare resources to manage chronic conditions have contributed to population-level increases in the cognitive functioning of older adults. However, research has not focused on older adults with chronic conditions such as diabetes.
Our objective was to compare the cognitive functioning of Mexican adults aged ≥60 with diabetes in 2001 and 2018.
Data came from Mexican Health and Aging Study. Our study used a cross-sectional design and included participants aged ≥60 with self-reported diabetes during the 2001 (n = 1,052, mean age = 68.4, female = 59.6%) and 2018 (n = 2,469, mean age = 70.6, female = 62.0%) observation waves. Five cognitive tests were used to create a score of global cognition. Generalized estimating equations were used to compare global cognition in 2001 to 2018.
Older adults in 2018 had more education and were more likely than older adults in 2001 to take oral medication for diabetes, insulin, and to check blood sugar weekly. Older adults in 2018 had higher global cognition than in 2001 when adjusting for age, gender, education, and health insurance coverage (b = 0.38, SE = 0.02). This statistically significant difference remained after adjusting for health conditions, health behaviors, and diabetes management behaviors.
Older adults in Mexico with self-reported diabetes in 2018 had higher cognitive function than in 2001. Future research is needed to investigate causes of the cohort differences in cognitive functioning among Mexican older adults with self-reported diabetes.
墨西哥≥60 岁成年人的 2 型糖尿病患病率几乎翻了一番。教育和医疗资源的增加有助于管理慢性病,这导致了老年人整体认知功能的提高。然而,研究并未关注患有糖尿病等慢性病的老年人。
我们的目的是比较 2001 年和 2018 年患有糖尿病的墨西哥≥60 岁成年人的认知功能。
数据来自墨西哥健康与老龄化研究。我们的研究采用了横断面设计,纳入了 2001 年(n=1052,平均年龄 68.4,女性占 59.6%)和 2018 年(n=2469,平均年龄 70.6,女性占 62.0%)有自我报告糖尿病的≥60 岁参与者。使用五项认知测试来创建总体认知评分。使用广义估计方程比较 2001 年和 2018 年的总体认知情况。
与 2001 年相比,2018 年的老年人受教育程度更高,更有可能服用口服糖尿病药物、胰岛素,并每周检查血糖。调整年龄、性别、教育程度和医疗保险覆盖范围后,2018 年老年人的总体认知高于 2001 年(b=0.38,SE=0.02)。在调整健康状况、健康行为和糖尿病管理行为后,这种统计学上的显著差异仍然存在。
2018 年自我报告患有糖尿病的墨西哥老年人的认知功能高于 2001 年。需要进一步研究以探讨墨西哥自我报告患有糖尿病的老年人群中认知功能的队列差异的原因。