Mejia-Arango Silvia, Avila Jaqueline, Downer Brian, Garcia Marc A, Michaels-Obregon Alejandra, Saenz Joseph L, Samper-Ternent Rafael, Wong Rebeca
Department of Population Studies, El Colegio de la Frontera Norte, Tijuana 22560, Baja California, Mexico.
Center for Alcohol and Addiction Studies, School of Public Health, Brown University, Providence, RI 02912, USA.
Geriatrics (Basel). 2021 Jun 25;6(3):63. doi: 10.3390/geriatrics6030063.
Sources of health disparities such as educational attainment, cardiovascular risk factors, and access to health care affect cognitive impairment among older adults. To examine the extent to which these counteracting changes affect cognitive aging over time among Mexican older adults, we examine how sociodemographic factors, cardiovascular diseases, and their treatment relate to changes in cognitive function of Mexican adults aged 60 and older between 2001 and 2015. Self and proxy respondents were classified as dementia, cognitive impairment no dementia (CIND), and normal cognition. We use logistic regression models to examine the trends in dementia and CIND for men and women aged 60 years or older using pooled national samples of 6822 individuals in 2001 and 10,219 in 2015, and sociodemographic and health variables as covariates. We found higher likelihood of dementia and a lower risk of CIND in 2015 compared to 2001. These results remain after adjusting for sociodemographic factors, cardiovascular diseases, and their treatment. The improvements in educational attainment, treatment of diabetes and hypertension, and better access to health care in 2015 compared to 2001 may not have been enough to counteract the combined effects of aging, rural residence disadvantage, and higher risks of cardiovascular disease among older Mexican adults.
教育程度、心血管危险因素和医疗保健可及性等健康差异来源会影响老年人的认知障碍。为了研究这些抵消性变化在一段时间内对墨西哥老年人认知衰老的影响程度,我们考察了社会人口学因素、心血管疾病及其治疗与2001年至2015年期间60岁及以上墨西哥成年人认知功能变化之间的关系。自我受访者和代理受访者被分为痴呆、无痴呆的认知障碍(CIND)和正常认知。我们使用逻辑回归模型,以2001年6822名个体和2015年10219名个体的全国汇总样本,以及社会人口学和健康变量作为协变量,来研究60岁及以上男性和女性痴呆和CIND的趋势。我们发现,与2001年相比,2015年患痴呆的可能性更高,患CIND的风险更低。在对社会人口学因素、心血管疾病及其治疗进行调整后,这些结果依然成立。与2001年相比,2015年教育程度的提高、糖尿病和高血压的治疗以及更好的医疗保健可及性可能不足以抵消墨西哥老年成年人衰老、农村居住劣势和心血管疾病更高风险的综合影响。