Charnsangavej C, Carrasco C H, Wallace S, Wright K C, Ogawa K, Richli W, Gianturco C
Radiology. 1986 Nov;161(2):295-8. doi: 10.1148/radiology.161.2.3763891.
To test the ability of Gianturco expandable metallic stents to dilate and maintain patency in stenotic venae cavae, stenosis of the inferior vena cava was created in seven mongrel dogs by the percutaneous injection of absolute ethanol into the paravascular retroperitoneal space. Gianturco stents, placed across the stenotic segment, resulted in successful dilatation with improved hemodynamics in four dogs. The stents failed to dilate an occluded vena cava in one dog; in the remaining dogs, stent placement was complicated by early migration and occlusion. Gianturco stents were placed in two patients, one with superior vena cava syndrome and one with retroperitoneal fibrosis that obstructed the inferior vena cava, and resulted in immediate relief of presenting symptoms. These results should be viewed cautiously, but further investigation into the clinical use of the stents is indicated, especially for patients for whom other treatments are difficult.
为测试Gianturco可扩张金属支架扩张狭窄腔静脉并维持其通畅的能力，通过经皮向血管旁腹膜后间隙注射无水乙醇，在7只杂种犬中造成下腔静脉狭窄。将Gianturco支架置于狭窄段，4只犬成功扩张，血流动力学得到改善。1只犬的支架未能扩张闭塞的腔静脉；其余犬中，支架置入出现早期移位和闭塞并发症。在2例患者中置入了Gianturco支架，1例患有上腔静脉综合征，1例患有腹膜后纤维化导致下腔静脉梗阻，置入后即刻缓解了当前症状。这些结果应谨慎看待，但表明有必要对支架的临床应用进行进一步研究，特别是对于其他治疗困难的患者。
