Emerg Infect Dis. 2023 Oct;29(10):2116-2120. doi: 10.3201/eid2910.230675. Epub 2023 Aug 28.
From 2015-2018 to 2019‒2021, hypertoxigenic M1 lineage among invasive group A Streptococcus increased in the United States (1.7%, 21/1,230 to 11%, 65/603; p<0.001). M1 was observed in 9 of 10 states, concentrated in Georgia (n = 41), Tennessee (n = 13), and New York (n = 13). Genomic cluster analysis indicated recent expansions.
从 2015-2018 年到 2019-2021 年,美国侵袭性 A 组链球菌中超毒力 M1 谱系的比例增加(1.7%,21/1230 至 11%,65/603;p<0.001)。M1 见于 10 个州中的 9 个,集中在佐治亚州(n=41)、田纳西州(n=13)和纽约州(n=13)。基因组聚类分析表明近期有扩张。