Center for Food Science and Nutrition, Addis Ababa University, Addis Ababa, Ethiopia
Sport Science Academy, Wollo University, Dessie, Ethiopia.
BMJ Open. 2023 Aug 28;13(8):e075893. doi: 10.1136/bmjopen-2023-075893.
In low-income countries, such as Ethiopia, few studies have evaluated the risk of cardiovascular disease (CVD) among hypertensive patients. We assessed the 10-year CVD risk of hypertensive patients.
This cross-sectional study was part of a larger survey conducted in Addis Ababa. The 10-year CVD risk was calculated using the Framingham Risk Score (FRS) algorithm based on seven sex-specific risk factors as well as a country-specific Globorisk score. Fruits and vegetables (FV) consumption, salt intake and stress levels were measured with 24-hour dietary recall, INTERSALT equation and Cohen's Perceived Stress Scale, respectively. A multiple linear regression model was fitted to explore the association.
Addis Ababa, Ethiopia, 2021.
A sample of 191 patients diagnosed with hypertension.
Predicted 10-year cardiovascular risk of hypertensive patients.
A total of 42.4%, 27.7% and 29.8% of hypertensive patients were at low, moderate and high CVD risks, respectively. The majority (80.1%) of patients consumed inadequate FV, 95.7% consumed salt >5 g/day and 58.1% had moderate to high-stress levels. There was a substantial agreement between the FRS and Globorisk prediction models (weighted kappa 0.77). In the unadjusted model, FV consumption (>450 g/day) and total fruit intake in the highest tertile were associated with 14.2% and 6.7% lower CVD risk, respectively. After adjusting for lifestyle factors, increasing FV intake from 120 to 450 g/day was significantly related to 11.1%-15.2% lower CVD risk in a dose-response manner. Additionally, total fruit, but not total vegetable intake in the highest tertile, was significantly associated with decreased CVD risk.
We found a high prevalence of CVD risk among hypertensive patients. High FV consumption was inversely associated with CVD risk. This suggests that patients should be advised to increase FV intake to minimise CVD risk.
在埃塞俄比亚等低收入国家,针对高血压患者的心血管疾病(CVD)风险评估研究较少。我们评估了高血压患者的 10 年 CVD 风险。
本横断面研究是在亚的斯亚贝巴进行的一项更大规模调查的一部分。使用基于七个性别特异性风险因素的 Framingham 风险评分(FRS)算法以及特定于国家的 Globorisk 评分来计算 10 年 CVD 风险。通过 24 小时膳食回忆、INTERSALT 方程和 Cohen 的感知压力量表分别测量水果和蔬菜(FV)摄入量、盐摄入量和压力水平。拟合多元线性回归模型以探索相关性。
埃塞俄比亚亚的斯亚贝巴,2021 年。
诊断为高血压的 191 名患者的样本。
共有 42.4%、27.7%和 29.8%的高血压患者处于低、中、高 CVD 风险,分别。大多数(80.1%)患者的 FV 摄入量不足,95.7%的患者盐摄入量>5g/天,58.1%的患者压力处于中度至高度。FRS 和 Globorisk 预测模型之间存在实质性一致性(加权kappa 0.77)。在未调整模型中,FV 摄入量(>450g/天)和最高 tertile 的总水果摄入量分别与 CVD 风险降低 14.2%和 6.7%相关。在调整生活方式因素后,FV 摄入量从 120 克增加到 450 克/天与 CVD 风险降低 11.1%-15.2%呈剂量反应关系。此外,总水果,而不是总蔬菜摄入量在最高 tertile 中,与降低 CVD 风险显著相关。
我们发现高血压患者的 CVD 风险患病率较高。高 FV 摄入量与 CVD 风险呈负相关。这表明应建议患者增加 FV 摄入量以最大限度地降低 CVD 风险。