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继发神经管缺陷:残留的脊髓。

Secondary Neurulation Defects: Retained Medullary Cord.

机构信息

Division of Pediatric Neurosurgery, Seoul National University Children's Hospital, Seoul, Republic of Korea.

Department of Neurosurgery, Seoul National University College of Medicine, Seoul, Republic of Korea.

出版信息

Adv Tech Stand Neurosurg. 2023;47:215-223. doi: 10.1007/978-3-031-34981-2_7.

DOI:10.1007/978-3-031-34981-2_7
PMID:37640876
Abstract

Retained medullary cord (RMC) is a defect resulting from impaired secondary neurulation. Intraoperatively, RMC is recognizable as an elongated cord-like structure caudal to the conus, that contains histologically confirmed neuroglial components and a lumen with an ependymal lining. It characteristically does not possess neurological function. This chapter aims to summarize (1) the mechanisms that lead to the occurrence of RMC; (2) the various forms of RMC, such as cystic RMC and 'possible RMC', and (3) the treatment strategies, especially untethering through limited exposure.

摘要

残留髓芯(RMC)是一种由于二次神经管化障碍而导致的缺陷。在手术中,RMC 表现为圆锥末端以下的细长索状结构,包含组织学证实的神经胶质成分和一个具有室管膜衬里的管腔。它通常不具备神经功能。本章旨在总结:(1)导致 RMC 发生的机制;(2)RMC 的各种形式,如囊性 RMC 和“可能的 RMC”;以及(3)治疗策略,特别是通过有限暴露进行松解。

相似文献

1
Secondary Neurulation Defects: Retained Medullary Cord.继发神经管缺陷:残留的脊髓。
Adv Tech Stand Neurosurg. 2023;47:215-223. doi: 10.1007/978-3-031-34981-2_7.
2
Secondary Neurulation Defects-1 : Retained Medullary Cord.继发性神经管缺陷-1:髓索残留
J Korean Neurosurg Soc. 2020 May;63(3):314-320. doi: 10.3340/jkns.2020.0052. Epub 2020 Apr 27.
3
Cystic retained medullary cord in an intraspinal J-shaped cul-de-sac: a lesion in the spectrum of regression failure during secondary neurulation.椎管内 J 形终池内囊性残留髓索:二次神经管化过程中退化失败的病变谱中的一种病变。
Childs Nerv Syst. 2021 Jun;37(6):2051-2056. doi: 10.1007/s00381-020-04943-6. Epub 2020 Oct 28.
4
Subpial Lumbar Lipoma Associated with Retained Medullary Cord.伴有脊髓残留的软膜下腰椎脂肪瘤
NMC Case Rep J. 2021 Apr 2;8(1):51-55. doi: 10.2176/nmccrj.cr.2020-0073. eCollection 2021 Apr.
5
Retained medullary cord with sacral subcutaneous meningocele and congenital dermal sinus.脊髓圆锥合并骶尾部皮下脊膜膨出和先天性皮窦。
Childs Nerv Syst. 2020 Feb;36(2):423-427. doi: 10.1007/s00381-019-04301-1. Epub 2019 Jul 11.
6
Ependyma-Lined Canal with Surrounding Neuroglial Tissues in Lumbosacral Lipomatous Malformations: Relationship with Retained Medullary Cord.腰骶部脂肪瘤样畸形中衬有室管膜的管腔及其周围神经胶质组织:与残留脊髓的关系
Pediatr Neurosurg. 2018;53(6):387-394. doi: 10.1159/000494029. Epub 2018 Nov 2.
7
Retained Medullary Cord Associated with Terminal Myelocystocele and Intramedullary Arachnoid Cyst.终丝髓脂肪瘤伴硬脊膜内蛛网膜囊肿相关的残留髓索
Pediatr Neurosurg. 2022;57(3):184-190. doi: 10.1159/000523976. Epub 2022 Mar 8.
8
Retained medullary cord and terminal myelocystocele as a spectrum: case report.保留的髓质和终末脊髓脊膜膨出作为一个谱系:病例报告。
Childs Nerv Syst. 2022 Jun;38(6):1223-1228. doi: 10.1007/s00381-021-05351-0. Epub 2021 Sep 17.
9
Two cases of retained medullary cord running parallel to a terminal lipoma.两例髓质脊髓残留与终丝脂肪瘤平行。
Surg Neurol Int. 2021 Mar 24;12:112. doi: 10.25259/SNI_626_2020. eCollection 2021.
10
Surgical histopathology of a filar anomaly as an additional tethering element associated with closed spinal dysraphism of primary neurulation failure.作为与原发性神经管形成失败导致的闭合性脊柱裂相关的额外栓系因素的丝虫异常的手术组织病理学。
Surg Neurol Int. 2021 Jul 27;12:373. doi: 10.25259/SNI_340_2021. eCollection 2021.

本文引用的文献

1
Disorders of Secondary Neurulation : Mainly Focused on Pathoembryogenesis.继发性神经管形成障碍:主要聚焦于病理胚胎发生
J Korean Neurosurg Soc. 2021 May;64(3):386-405. doi: 10.3340/jkns.2021.0023. Epub 2021 Apr 29.
2
Two cases of retained medullary cord running parallel to a terminal lipoma.两例髓质脊髓残留与终丝脂肪瘤平行。
Surg Neurol Int. 2021 Mar 24;12:112. doi: 10.25259/SNI_626_2020. eCollection 2021.
3
Cystic retained medullary cord in an intraspinal J-shaped cul-de-sac: a lesion in the spectrum of regression failure during secondary neurulation.
椎管内 J 形终池内囊性残留髓索:二次神经管化过程中退化失败的病变谱中的一种病变。
Childs Nerv Syst. 2021 Jun;37(6):2051-2056. doi: 10.1007/s00381-020-04943-6. Epub 2020 Oct 28.
4
Terminal Myelocystocele : Pathoembryogenesis and Clinical Features.终末脊髓脊膜膨出:病理胚胎发生及临床特征
J Korean Neurosurg Soc. 2020 May;63(3):321-326. doi: 10.3340/jkns.2020.0063. Epub 2020 Apr 27.
5
Spinal Dysraphism in the Last Two Decades : What I Have Seen during the Era of Dynamic Advancement.过去二十年的脊柱裂:动态进步时代的所见所闻
J Korean Neurosurg Soc. 2020 May;63(3):272-278. doi: 10.3340/jkns.2020.0068. Epub 2020 Apr 27.
6
Secondary Neurulation Defects-1 : Retained Medullary Cord.继发性神经管缺陷-1:髓索残留
J Korean Neurosurg Soc. 2020 May;63(3):314-320. doi: 10.3340/jkns.2020.0052. Epub 2020 Apr 27.
7
Retained medullary cord with sacral subcutaneous meningocele and congenital dermal sinus.脊髓圆锥合并骶尾部皮下脊膜膨出和先天性皮窦。
Childs Nerv Syst. 2020 Feb;36(2):423-427. doi: 10.1007/s00381-019-04301-1. Epub 2019 Jul 11.
8
Filar cysts in rare cases may progress in size, particularly when associated with filar lipoma.在罕见情况下,丝状囊肿可能会增大,尤其是与丝状脂肪瘤相关时。
Childs Nerv Syst. 2019 Jul;35(7):1207-1211. doi: 10.1007/s00381-019-04148-6. Epub 2019 Apr 10.
9
Enlargement of sacral subcutaneous meningocele associated with retained medullary cord.骶部皮下脊膜膨出伴脊髓栓系扩大。
Childs Nerv Syst. 2018 Sep;34(9):1785-1790. doi: 10.1007/s00381-018-3812-z. Epub 2018 Apr 27.
10
Retained medullary cord extending to a sacral subcutaneous meningocele.残留的脊髓延伸至骶部皮下脊膜膨出。
Childs Nerv Syst. 2018 Mar;34(3):527-533. doi: 10.1007/s00381-017-3644-2. Epub 2017 Nov 3.