Lee Ji Yeoun, Kim Kyung Hyun, Wang Kyu-Chang
Division of Pediatric Neurosurgery, Seoul National University Children's Hospital, Seoul, Korea.
Department of Anatomy and Cell Biology, Seoul National University College of Medicine, Seoul, Korea.
J Korean Neurosurg Soc. 2020 May;63(3):321-326. doi: 10.3340/jkns.2020.0063. Epub 2020 Apr 27.
There has been confusion in the classification of terminal myelocystocele (TMCC) due to its diverse morphology and vague pathoembryogenesis. TMCC could be summarized as having the essential features of an elongated caudal spinal cord extruding out of the dorsal extraspinal space that fuses with the subcutaneous fat, which is in the shape of a trumpet-shaped cerebrospinal fluid-filled cyst. The extraspinal portion of the extruded spinal cord is nonfunctional. The morphological features suggest that TMCC is formed during secondary neurulation, specifically the failure of the degeneration of the secondary neural tube near the time of the terminal balloon. This review discusses the definition, as well as the clinical and surgical features, of TMCC with special emphasis on its pathoembryogenesis.
由于终末脊髓脊膜膨出（TMCC）形态多样且病理胚胎发生过程模糊，其分类一直存在混淆。TMCC可概括为具有以下基本特征：细长的尾侧脊髓从背侧脊柱外间隙挤出，与皮下脂肪融合，形成一个喇叭形充满脑脊液的囊肿。挤出脊髓的脊柱外部分无功能。形态学特征表明TMCC是在继发性神经管形成过程中形成的，特别是在终末球囊期附近继发性神经管退化失败。本文综述了TMCC的定义、临床及手术特征，并特别强调其病理胚胎发生过程。
