Department of Internal Medicine, Dow University of Health Sciences, Karachi, Pakistan.
Department of Internal Medicine, Jinnah Sindh Medical University, Karachi, Pakistan.
Disaster Med Public Health Prep. 2023 Aug 29;17:e464. doi: 10.1017/dmp.2023.128.
Monkeypox (MPX) is a rare zoonotic illness, like smallpox, caused by the monkeypox virus, which is a member of the Orthopoxvirus genus of the Chordopoxvirinae subfamily that falls under the classification of the Poxviridae family. MPX is clinically characterized by a wide variety of symptoms and signs, including fever, sore throat, headache, myalgia, lymphadenopathy, and rashes. As the world is undergoing progressive industrialization over time, there is a corresponding increase in environmental pollutants and deforestation. Previous studies have found a correlation between exposure to environmental contaminants and the incidence of MPX. Additionally, it has been hypothesized that deforestation may also have played a role in the disease's resurgence or in its ability to spread. Habitat loss and ecological instability brought on by environmental contaminants and deforestation may increase human-infected animal interaction and hasten the spread. The likely connection should be known by health authorities and doctors, as well as government officials, to help fund further investigations and craft strategies to combat the risk of an increasing prevalence of MPX in the world, especially in densely populated underdeveloped regions of Asia and Africa, where containment of MPX poses greater challenges. In this article, we have provided an important real-world perspective and suggested future recommendations to halt the further spread of MPX to new places.
猴痘（MPX）是一种罕见的人畜共患病，与天花类似，由猴痘病毒引起，该病毒属于正痘病毒科痘病毒属的痘病毒亚科，属于痘病毒科。MPX 的临床特征是症状和体征多种多样，包括发热、咽痛、头痛、肌痛、淋巴结病和皮疹。随着世界的工业化进程不断推进，环境污染物和森林砍伐的数量也相应增加。先前的研究发现，暴露于环境污染物与 MPX 的发病率之间存在关联。此外，有人假设森林砍伐也可能在疾病的再次出现或传播能力方面发挥了作用。环境污染物和森林砍伐导致的栖息地丧失和生态不稳定可能会增加人类感染动物的相互作用，并加速疾病的传播。卫生当局和医生以及政府官员应该了解这种可能的联系，以帮助为进一步的调查提供资金，并制定策略来应对 MPX 在全球范围内（特别是在人口稠密的欠发达的亚洲和非洲地区）发病率不断上升的风险，在这些地区控制 MPX 面临更大的挑战。在本文中，我们提供了一个重要的现实观点，并提出了未来的建议，以阻止 MPX 进一步传播到新的地方。
