Washington University School of Medicine, St. Louis, Missouri.
Division of Dermatology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri.
Dermatol Surg. 2023 Dec 1;49(12):1091-1095. doi: 10.1097/DSS.0000000000003921. Epub 2023 Aug 29.
Primary cutaneous mucinous carcinoma (PCMC) is an exceedingly rare, low-grade tumor that histologically resembles mucinous carcinoma from other primary sites, such as the breast, gastrointestinal tract, and lungs.
The purpose of this article was to review the current literature on PCMC as it relates to epidemiology, clinical presentation, histopathology, immunohistochemistry, treatment, and prognosis.
An extensive literature review was conducted using PubMed and Ovid MEDLINE to identify articles related to PCMC.
Several hundred cases have been reported in the medical literature, and surgical resection, whenever feasible, is the standard of care.
The diagnosis of primary cutaneous mucinous carcinoma is one of exclusion, requiring a metastatic work-up to rule out distant primary. Mohs micrographic surgery is a tissue sparing technique that allows complete margin control of these rare neoplasia.
原发性皮肤黏液腺癌（PCMC）是一种极其罕见的低度恶性肿瘤，组织学上类似于来自其他原发性部位的黏液腺癌，如乳腺、胃肠道和肺部。
本文旨在回顾与 PCMC 相关的流行病学、临床表现、组织病理学、免疫组织化学、治疗和预后的现有文献。
使用 PubMed 和 Ovid MEDLINE 进行广泛的文献回顾，以确定与 PCMC 相关的文章。
在医学文献中已经报道了数百例病例，只要可行，手术切除就是标准的治疗方法。
原发性皮肤黏液腺癌的诊断是一种排除性诊断，需要进行转移灶检查以排除远处原发性肿瘤。Mohs 显微外科手术是一种保留组织的技术，可实现对这些罕见肿瘤的完全边缘控制。
