一种对用铟-111标记的粗制白细胞悬液进行粒细胞富集的简单方法。

A simple method of granulocyte enrichment of crude white cell suspensions labelled with 111In.

作者信息

Schmidt K G, Rasmussen J W, Thaisen K, Wedebye I M

出版信息

Scand J Haematol. 1986 Aug;37(2):144-50. doi: 10.1111/j.1600-0609.1986.tb01788.x.

DOI:10.1111/j.1600-0609.1986.tb01788.x

Abstract

A simple method of granulocyte enrichment of a 111In-labelled mixed white cell suspension is described. The method rests on preferential sedimentation by gravity of the granulocytes during labelling. In the 50 studies performed, the granulocytes constituted on average 90% of the 111In-labelled white cells injected for abscess detection. The modest degree of artefactual granulocyte pooling in the lungs and the results of the scintigraphic studies suggest that the method described is well-suited for scintigraphic localization of infectious and inflammatory processes.

摘要

本文描述了一种简单的方法，用于对铟-111标记的混合白细胞悬液进行粒细胞富集。该方法基于在标记过程中粒细胞通过重力进行优先沉降。在进行的50项研究中，粒细胞平均占注入用于脓肿检测的铟-111标记白细胞的90%。肺部粒细胞的适度人为聚集程度以及闪烁扫描研究结果表明，所描述的方法非常适合用于感染和炎症过程的闪烁扫描定位。