文献检索文档翻译深度研究
Suppr Zotero 插件Zotero 插件
邀请有礼套餐&价格历史记录

新学期,新优惠

限时优惠:9月1日-9月22日

30天高级会员仅需29元

1天体验卡首发特惠仅需5.99元

了解详情
不再提醒
插件&应用
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
高级版
套餐订阅购买积分包
AI 工具
文献检索文档翻译深度研究
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2025

正电子发射断层扫描/计算机断层扫描对髋关节假体周围感染的诊断准确性:系统评价和荟萃分析。

Diagnostic accuracy of positron emission tomography/computerized tomography for periprosthetic joint infection of hip: systematic review and meta-analysis.

机构信息

Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, Taiyuan, 030032, China.

Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.

出版信息

J Orthop Surg Res. 2023 Aug 30;18(1):640. doi: 10.1186/s13018-023-04061-4.


DOI:10.1186/s13018-023-04061-4
PMID:37644493
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10466775/
Abstract

BACKGROUND: American Academy of Orthopaedic Surgeons (AAOS) has provided the guidelines for diagnosing a patient with periprosthetic joint infection including the use of positron emission tomography/computed tomography (PET/CT). Systematic evidence focussing on periprosthetic joint infection (PJI) of hip is limited, which also contains limited number of studies. Hence, the current study aims to perform a pooled analysis of all studies that have assessed the diagnostic accuracy of PET/CT for PJI of hip. METHODS: Searches were done in PubMed Central, EMBASE, MEDLINE, SCOPUS and Cochrane library until December 2022. Meta-analysis was carried out using random-effects model. With 95% confidence intervals (CIs), pooled sensitivity and specificity were reported. RESULTS: Twenty-six studies met the inclusion criteria. The pooled sensitivity of PET/CT was 89% (95% CI 84-93%), while the pooled specificity was 86% (95% CI 79-91%). The AUROC was 0.94 (95% CI 0.72-0.99). There was statistically significant heterogeneity (p < 0.001) with I2 value of 96%. The diagnostic odds ratio was 52 (95% CI 26-106). Likelihood ratio positive was 6.5 (95% CI 4.1-10.3) and negative was 0.13 (95% CI 0.08-0.19). CONCLUSION: Our study found that PET/CT was found to have higher level of accuracy in terms of sensitivity and specificity. Further large-scale research can help to find answers for such questions and provide final conclusive evidence on the inclusion of the imaging modality into the routine clinical practice guidelines for suspected periprosthetic joint infection patients.

摘要

背景:美国骨科医师学会(AAOS)已经提供了诊断人工关节周围感染患者的指南,包括使用正电子发射断层扫描/计算机断层扫描(PET/CT)。针对髋关节人工关节周围感染(PJI)的系统证据有限,且其中包含的研究数量也有限。因此,本研究旨在对所有评估 PET/CT 对髋关节 PJI 诊断准确性的研究进行汇总分析。

方法:在 PubMed Central、EMBASE、MEDLINE、SCOPUS 和 Cochrane 图书馆进行检索,检索时间截至 2022 年 12 月。使用随机效应模型进行荟萃分析。以 95%置信区间(CI)报告汇总敏感性和特异性。

结果:26 项研究符合纳入标准。PET/CT 的汇总敏感性为 89%(95%CI 84-93%),而汇总特异性为 86%(95%CI 79-91%)。AUROC 为 0.94(95%CI 0.72-0.99)。存在统计学显著的异质性(p<0.001),I2 值为 96%。诊断比值比为 52(95%CI 26-106)。阳性似然比为 6.5(95%CI 4.1-10.3),阴性似然比为 0.13(95%CI 0.08-0.19)。

结论:我们的研究发现,PET/CT 在敏感性和特异性方面具有更高的准确性水平。进一步的大规模研究可以帮助回答这些问题,并为将该影像学方法纳入疑似人工关节周围感染患者的常规临床实践指南提供最终确凿证据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1239/10466775/61641c6f1103/13018_2023_4061_Fig9_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1239/10466775/8eb7b90ee057/13018_2023_4061_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1239/10466775/1f01249e1a07/13018_2023_4061_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1239/10466775/a4edb45fbc13/13018_2023_4061_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1239/10466775/c04490eb847a/13018_2023_4061_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1239/10466775/01dfe7b9fa8e/13018_2023_4061_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1239/10466775/29fbbdb3b4db/13018_2023_4061_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1239/10466775/73108fa56e18/13018_2023_4061_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1239/10466775/318790ce0f8b/13018_2023_4061_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1239/10466775/61641c6f1103/13018_2023_4061_Fig9_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1239/10466775/8eb7b90ee057/13018_2023_4061_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1239/10466775/1f01249e1a07/13018_2023_4061_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1239/10466775/a4edb45fbc13/13018_2023_4061_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1239/10466775/c04490eb847a/13018_2023_4061_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1239/10466775/01dfe7b9fa8e/13018_2023_4061_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1239/10466775/29fbbdb3b4db/13018_2023_4061_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1239/10466775/73108fa56e18/13018_2023_4061_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1239/10466775/318790ce0f8b/13018_2023_4061_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1239/10466775/61641c6f1103/13018_2023_4061_Fig9_HTML.jpg

相似文献

[1]
Diagnostic accuracy of positron emission tomography/computerized tomography for periprosthetic joint infection of hip: systematic review and meta-analysis.

J Orthop Surg Res. 2023-8-30

[2]
A Systematic Review and Meta-Analysis on the Accuracy of Fluorodeoxyglucose Positron Emission Tomography/ Computerized Tomography for Diagnosing Periprosthetic Joint Infections.

Front Surg. 2022-6-1

[3]
Fluorodeoxyglucose positron emission tomography imaging for diagnosing periprosthetic hip infection: the importance of diagnostic criteria.

Int Orthop. 2018-9

[4]
A systematic review and meta-analysis of F-fluorodeoxyglucose positron emission tomography or positron emission tomography/computed tomography for detection of infected prosthetic vascular grafts.

J Vasc Surg. 2019-3-25

[5]
Folic acid supplementation and malaria susceptibility and severity among people taking antifolate antimalarial drugs in endemic areas.

Cochrane Database Syst Rev. 2022-2-1

[6]
Diagnostic role of PET or PET/CT for prosthetic joint infection: A systematic review and Meta-analysis.

Hell J Nucl Med. 2021

[7]
The Accuracy of Imaging Techniques in the Assessment of Periprosthetic Hip Infection: A Systematic Review and Meta-Analysis.

J Bone Joint Surg Am. 2016-10-5

[8]
What is the Accuracy of Nuclear Imaging in the Assessment of Periprosthetic Knee Infection? A Meta-analysis.

Clin Orthop Relat Res. 2017-5

[9]
Utility of intraoperative frozen section histopathology in the diagnosis of periprosthetic joint infection: a systematic review and meta-analysis.

J Bone Joint Surg Am. 2012-9-19

[10]
A systematic review and meta-analysis of F-fluoro-d-deoxyglucose positron emission tomography interpretation methods in vascular graft and endograft infection.

J Vasc Surg. 2020-12

引用本文的文献

[1]
Correction: Diagnostic accuracy of positron emission tomography/computerized tomography for periprosthetic joint infection of hip: systematic review and meta-analysis.

J Orthop Surg Res. 2023-11-14

本文引用的文献

[1]
Bacterial pathogens and in-hospital mortality in revision surgery for periprosthetic joint infection of the hip and knee: analysis of 346 patients.

Eur J Med Res. 2023-5-19

[2]
Application of Ga-citrate PET/CT for differentiating periprosthetic joint infection from aseptic loosening after joint replacement surgery.

Bone Joint Res. 2022-6

[3]
A Systematic Review and Meta-Analysis on the Accuracy of Fluorodeoxyglucose Positron Emission Tomography/ Computerized Tomography for Diagnosing Periprosthetic Joint Infections.

Front Surg. 2022-6-1

[4]
The Role of Nuclear Medicine Imaging with F-FDG PET/CT, Combined In-WBC/Tc-Nanocoll, and Tc-HDP SPECT/CT in the Evaluation of Patients with Chronic Problems after TKA or THA in a Prospective Study.

Diagnostics (Basel). 2022-3-10

[5]
Projections for primary hip and knee replacement surgery up to the year 2060: an analysis based on data from The National Joint Registry for England, Wales, Northern Ireland and the Isle of Man.

Ann R Coll Surg Engl. 2022-6

[6]
The Role of Imaging Techniques to Define a Peri-Prosthetic Hip and Knee Joint Infection: Multidisciplinary Consensus Statements.

J Clin Med. 2020-8-6

[7]
An update on the role of F-FDG-PET/CT in major infectious and inflammatory diseases.

Am J Nucl Med Mol Imaging. 2019-12-15

[8]
Diagnosis and Prevention of Periprosthetic Joint Infections.

J Am Acad Orthop Surg. 2020-4-15

[9]
Diagnostic utility of fluorodeoxyglucose positron emission tomography in prosthetic joint infection based on MSIS criteria.

Bone Joint J. 2019-8

[10]
Potential usefulness of Ga-citrate PET/CT in detecting infected lower limb prostheses.

EJNMMI Res. 2019-1-3

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

推荐工具

医学文档翻译智能文献检索