Blackburn W D, Dunn T L, Alarcón G S
South Med J. 1986 Oct;79(10):1238-41. doi: 10.1097/00007611-198610000-00011.
Septic arthritis is a serious and sometimes fatal complication of rheumatoid arthritis. We have examined the clinical characteristics of 16 patients with infectious arthritis seen during an eight-year period. This represented 0.5% of all admissions to our hospital for patients with rheumatoid arthritis. Although rheumatoid arthritis is considered a predisposing factor for joint sepsis, 15 of our patients had other conditions that most likely increased their susceptibility to infection. Many patients lacked distinctive features of joint sepsis (fever, chills) and only one half had leukocytosis. Six had polyarticular complaints despite documented monarthric sepsis. Delay in diagnosis of joint infection and persistent effusions of the infected joints portended a poor prognosis.
感染性关节炎是类风湿关节炎的一种严重且有时会致命的并发症。我们对8年间收治的16例感染性关节炎患者的临床特征进行了研究。这占我院类风湿关节炎患者总入院人数的0.5%。尽管类风湿关节炎被认为是关节脓毒症的一个易感因素，但我们的15例患者还有其他状况，极有可能增加了他们对感染的易感性。许多患者缺乏关节脓毒症的典型特征（发热、寒战），只有一半患者有白细胞增多症。尽管已确诊为单关节脓毒症，但仍有6例患者有多关节症状。关节感染诊断延误以及感染关节持续存在积液预示预后不良。
