Schanz Caitlin C, Layden Mark P, DeSimone Daniel C, Stevens Ryan W, Clement Josh
Department of Pharmacy Services, Mayo Clinic, Rochester, United States.
Division of Public Health, Infectious Disease, and Occupational Medicine, Mayo Clinic, Rochester, United States.
IDCases. 2023 Jun 12;33:e01818. doi: 10.1016/j.idcr.2023.e01818. eCollection 2023.
is an anaerobic, gram-positive coccus rarely identified as a pathogenic organism. However, case reports have suggested as a causative pathogen in bacteremia, nosocomial pneumonia, ventilator-associated pneumonia, synovitis, cholecystitis, and ophthalmologic infections. Herein, we present the first case of causing native mitral valve infective endocarditis. With the exception of erythromycin, the isolate displayed favorable minimum inhibitory concentrations (MIC) to all other antibiotics tested, including beta-lactams, levofloxacin, and vancomycin. The patient was successfully treated with a 6-week course of intravenous (IV) ceftriaxone followed by robotically assisted cardiac valve repair.
是一种厌氧革兰氏阳性球菌，很少被鉴定为致病生物。然而，病例报告表明它是菌血症、医院获得性肺炎、呼吸机相关性肺炎、滑膜炎、胆囊炎和眼科感染的致病病原体。在此，我们报告首例导致原发性二尖瓣感染性心内膜炎的病例。除红霉素外，该分离株对所有其他测试抗生素（包括β-内酰胺类、左氧氟沙星和万古霉素）均显示出良好的最低抑菌浓度（MIC）。患者接受了为期6周的静脉注射头孢曲松治疗，随后进行了机器人辅助心脏瓣膜修复，治疗成功。
